AMPDB_9625 | CHANNEL_COLICIN domain-containing protein

PEPTIDE SUMMARY

CHANNEL_COLICIN domain-containing protein

1 General Description

AMPDB ID: AMPDB_9625

Protein Names: CHANNEL_COLICIN domain-containing protein

Protein Family: Channel forming colicin family

Gene Name: HA48_21160

Source Organism: Pantoea wallisii

Protein Length: 285 AA

Protein Existence: Inferred from homology

2 Protein Sequence & Composition

2.1 Sequence

MAKATKADGNWDAGWQPGSLGFLELTVVNKPHQHPFEGRLGNLAELPLRPAGSTVGAMTNDFVLWFPMGSNLEPLYVAFTTILPAGPLKNRADQQAAAQTKIDVQRMQDAAKSVVDFYQLATDRAGAQATKAAQELASQVKGKTVRNAEQALAAFNKYKDVLNKKYSLADREAIAKALDATNMQTLANNLKRLSRGLGYTSKLFDASTIIKEARNALRSGDWKPFFVTVGSMYAGQQATALTALAFSALLTTPMGIVGYVFLLMAVNSFVGDTFTTELKKLAGVQ

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 43, 'R': 11, 'N': 14, 'D': 14, 'C': 0, 'Q': 16, 'E': 9, 'G': 21, 'H': 2, 'I': 6, 'L': 32, 'K': 20, 'M': 8, 'F': 14, 'P': 11, 'S': 13, 'T': 22, 'W': 4, 'Y': 7, 'V': 18

Frequencies of Amino Acids

'A': 15.09%, 'R': 3.86%, 'N': 4.91%, 'D': 4.91%, 'C': 0%, 'Q': 5.61%, 'E': 3.16%, 'G': 7.37%, 'H': 0.7%, 'I': 2.11%, 'L': 11.23%, 'K': 7.02%, 'M': 2.81%, 'F': 4.91%, 'P': 3.86%, 'S': 4.56%, 'T': 7.72%, 'W': 1.4%, 'Y': 2.46%, 'V': 6.32%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

157

Hydrophilic Amino Acid(s) Count

128

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	30755.3 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	85.404	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	22.272	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.098	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.797	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	10.115	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	8.19	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.284, 0.207, 0.323 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.088	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	32430, 32430	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Palmer M, Steenkamp ET, Coetzee MPA, et al. Phylogenomic resolution of the bacterial genus Pantoea and its relationship with Erwinia and Tatumella. Antonie Van Leeuwenhoek. 2017;110(10):1287-1309. Published 2017 Oct. doi:10.1007/s10482-017-0852-4

PMID: 28255640

5.2 Protein Sequence Databases

UniProt: A0A1X1CU66

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A1X1CU66

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	MLFS01000105	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR000293, IPR038283, IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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