AMPDB_936 | Epidermal growth factor-like protein

PEPTIDE SUMMARY

Epidermal growth factor-like protein

1 General Description

AMPDB ID: AMPDB_936

Protein Names: Epidermal growth factor-like protein (LPS recognition protein) (LPR)

Protein Family: Nil

Gene Name: EGF-like

Source Organism: Holotrichia diomphalia (Korean black chafer)

Protein Length: 317 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MDFKIFLFLTAIFMIVGVTVSTATTNPTAPRAYRPRINTTAGVCELEVPIVNILPPELKHTAHTIRGNGSAPGFSKIKICCSGYKIVAHTPFHCTPDCPSGCGLGNCTAPNVCTCNKGAGFGPDGKCISVCPGRCLNGQCYGNFCNCNSGFVLEPNGRYCTGGCTRNCGPGGQCVGNNQCSCLSGFALNSQGTCQMICAPGFQQMGSACEPLCPKGCVNGECVAPGQCRCKSGYALNSSKVCAPKCSQPCYNGFCSAPNVCTCKEGYIKDATSRNGNRCIAYCAAGCPNGTCSAPNFCICKQGYIKQSKGSNVCVKQ

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 22, 'R': 10, 'N': 25, 'D': 4, 'C': 42, 'Q': 12, 'E': 7, 'G': 39, 'H': 4, 'I': 16, 'L': 12, 'K': 17, 'M': 4, 'F': 13, 'P': 24, 'S': 20, 'T': 20, 'W': 0, 'Y': 9, 'V': 17

Frequencies of Amino Acids

'A': 6.94%, 'R': 3.15%, 'N': 7.89%, 'D': 1.26%, 'C': 13.25%, 'Q': 3.79%, 'E': 2.21%, 'G': 12.3%, 'H': 1.26%, 'I': 5.05%, 'L': 3.79%, 'K': 5.36%, 'M': 1.26%, 'F': 4.1%, 'P': 7.57%, 'S': 6.31%, 'T': 6.31%, 'W': 0%, 'Y': 2.84%, 'V': 5.36%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

D, H, M

Hydrophobic Amino Acid(s) Count

147

Hydrophilic Amino Acid(s) Count

170

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	33037.2 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	56.94	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	25.064	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.032	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.601	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	8.27	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	13.76	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.211, 0.341, 0.142 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.069	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	13410, 16035	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Anti-candida, Anti-gram-negative

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Ju JS, Cho MH, Brade L, et al. A novel 40-kDa protein containing six repeats of an epidermal growth factor-like domain functions as a pattern recognition protein for lipopolysaccharide. J Immunol. 2006;177(3):1838-45. Published 2006 Aug 1. doi:10.4049/jimmunol.177.3.1838

PMID: 16849495

5.2 Protein Sequence Databases

UniProt: Q1HAY7

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: Q1HAY7

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	AB201466	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR000742, IPR009030

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

Download