AMPDB_910 | Theta defensin subunit A
PEPTIDE SUMMARY
Theta defensin subunit A
1 General Description
AMPDB ID: AMPDB_910
Protein Names: Theta defensin subunit A
Protein Family: Alpha-defensin family; Theta subfamily
Gene Name: Nil
Protein Length: 9 AA
Protein Existence: Evidence at protein level
2 Protein Sequence & Composition
2.1 Sequence
RCVCTRGFC
FASTA format
2.2 Composition
Counts of Amino Acids
'A': 0, 'R': 2, 'N': 0, 'D': 0, 'C': 3, 'Q': 0, 'E': 0, 'G': 1, 'H': 0, 'I': 0, 'L': 0, 'K': 0, 'M': 0, 'F': 1, 'P': 0, 'S': 0, 'T': 1, 'W': 0, 'Y': 0, 'V': 1
Frequencies of Amino Acids
'A': 0%, 'R': 22.22%, 'N': 0%, 'D': 0%, 'C': 33.33%, 'Q': 0%, 'E': 0%, 'G': 11.11%, 'H': 0%, 'I': 0%, 'L': 0%, 'K': 0%, 'M': 0%, 'F': 11.11%, 'P': 0%, 'S': 0%, 'T': 11.11%, 'W': 0%, 'Y': 0%, 'V': 11.11%
Missing Amino Acid(s)
A, D, E, H, I, K, L, M, N, P, Q, S, W, Y
Most Occurring Amino Acid(s)
C
Less Occurring Amino Acid(s)
F, G, T, V
Hydrophobic Amino Acid(s) Count
3
Hydrophilic Amino Acid(s) Count
6
Basic Amino Acid(s) Count
0
Acidic Amino Acid(s) Count
2
Modified Amino Acid(s) Count
0
Modified Amino Acid(s) Frequencies
0
Computed by biopython (version 1.79) & proteinAnalysis (version 1)
3 Physicochemical Properties
Sl. No. Properties Values Reference
1. Molecular Mass 1044.27 Da Computed by ProtParam module (biopython 1.79)
2. Aliphatic Index 32.222 Computed by ProtParam module (biopython 1.79)
3. Instability Index (Half Life) 27.3 Computed by ProtParam module (biopython 1.79)
4. Hydrophobicity (GRAVY) 0.489 Computed by ProtParam module (biopython 1.79)
5. Hydrophobic Moment 0.29 Computed by ProtParam module (biopython 1.79)
6. Isoelectric Point 8.525 Computed by ProtParam module (biopython 1.79)
7. Charge (at pH 7) 1.812 Computed by ProtParam module (biopython 1.79)
8. Secondary Structure Fraction 0.222, 0.111, 0 [Helix, Turn, Sheet] Computed by ProtParam module (biopython 1.79)
9. Aromaticity 0.111 Computed by ProtParam module (biopython 1.79)
10. Molar Extinction Coefficient (cysteine|cystine) 0, 125 Computed by ProtParam module (biopython 1.79)
4 Activity Details
4.1 Target Organism(s)
C.albicans, E.coli (Gram-negative), L.monocytogenes (Gram-positive), S.aureus (Gram-positive)
4.2 Antimicrobial Activity
Antibiotic, Antimicrobial, Defensin, Fungicide, Anti-MRSA, Anti-candida, Anti-gram-negative, Anti-gram-Positive
4.3 Enzymatic Activity
Not found
4.4 Inhibitory Effect
Not found
4.5 Other Biological Activity
Non-hemolytic, Non-ribosomal
Activity data manually curated from Literature and UniProt
5 Database Cross-references
5.1 Literature Database
5.1.1 PubMed
Citation 1: Stegemann C, Tsvetkova EV, Aleshina GM, et al. De novo sequencing of two new cyclic theta-defensins from baboon (Papio hamadryas) leukocytes by matrix-assisted laser desorption/ionization mass spectrometry. Rapid Commun Mass Spectrom. 2010;24(5):599-604. Published 2010 Mar 15. doi:10.1002/rcm.4424
PMID: 20155756
5.2 Protein Sequence Databases
UniProt: P86722
5.3 3D Structure Databases
No PDB Ids found
AlphaFoldDB: P86722
5.4 Nucleotide Sequence Databases
No entries found in GenBank or EMBL
CCDS: Not found
RefSeq: Not found
5.5 Protein-Protein Interaction Databases
STRING: Not found
IntAct: Not found
MINT: Not found
DIP: Not found
BioGRID: Not found
5.6 Ligand Databases
BindingDB: Not found
DrugBank: Not found
ChEMBL: Not found
5.7 Family & Domain Databases
InterPro: Not found
PANTHER: Not found
PROSITE: Not found
5.8 Genome Annotation Databases
Ensembl: Not found
KEGG: Not found
5.9 Phylogenomic Databases
GeneTree: Not found
5.10 Enzyme & Pathway Databases
BRENDA: Not found
BioCyc: Not found
5.11 Protein-RNA Interaction Databases
RNAct: Not found




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