AMPDB_902 | Seed lectin alpha chain

PEPTIDE SUMMARY

Seed lectin alpha chain

1 General Description

AMPDB ID: AMPDB_902

Protein Names: Seed lectin alpha chain

Protein Family: Leguminous lectin family

Gene Name: Nil

Source Organism: Spatholobus parviflorus (Butea parviflora)

Protein Length: 251 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

AEETSFVFSKFKPLEPNLILQGDALVTVAGVLQLTNVDKNGVPEPSSLGRATYSAPINIWDSATGLVASFATSFRFTIYAPNIATIADGLAFFLAPVASAPDSGGGFLGLFDSAVSGSTYQTVAVEFDTYENTVFTDPPYTHIGFDVNSISSIKTVKWSLANGEAAKVLITYNSAVKLLVASLVYPSSKTSFILADIVDLSSVLPEWVRVGFSAATGASGGKIETHDVFSWSFASKLAGXXTKDSSFLDGG

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 28, 'R': 3, 'N': 9, 'D': 14, 'C': 0, 'Q': 3, 'E': 9, 'G': 20, 'H': 2, 'I': 13, 'L': 22, 'K': 11, 'M': 0, 'F': 18, 'P': 12, 'S': 31, 'T': 20, 'W': 4, 'Y': 7, 'V': 23

Frequencies of Amino Acids

'A': 11.16%, 'R': 1.2%, 'N': 3.59%, 'D': 5.58%, 'C': 0%, 'Q': 1.2%, 'E': 3.59%, 'G': 7.97%, 'H': 0.8%, 'I': 5.18%, 'L': 8.76%, 'K': 4.38%, 'M': 0%, 'F': 7.17%, 'P': 4.78%, 'S': 12.35%, 'T': 7.97%, 'W': 1.59%, 'Y': 2.79%, 'V': 9.16%

Missing Amino Acid(s)

C, M

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

H, X

Hydrophobic Amino Acid(s) Count

140

Hydrophilic Amino Acid(s) Count

109

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

{'X': 2}

Modified Amino Acid(s) Frequencies

{'X': 0.00796812749003984}

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	26150.4 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	92.112	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	32.159	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.301	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.621	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	4.354	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-8.807	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.347, 0.287, 0.235 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.116	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	32430, 32430	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

A.flavus (Not characterize)

4.2 Antimicrobial Activity

Antimicrobial, Fungicide

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Lectin, Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Abhilash J, Dileep KV, Palanimuthu M, et al. Metal ions in sugar binding, sugar specificity and structural stability of Spatholobus parviflorus seed lectin. J Mol Model. 2013;19(8):3271-8. Published 2013 Aug. doi:10.1007/s00894-013-1854-4

PMID: 23652482

Citation 2: Tintu I, Abhilash J, Dileep KV, et al. A lectin from Spatholobus parviflorus inhibits Aspergillus flavus Î±-amylase: enzyme kinetics and thermodynamic studies. Chem Biol Drug Des. 2014;84(1):116-22. Published 2014 Jul. doi:10.1111/cbdd.12291

PMID: 24460654

Citation 3: Geethanandan K, Abhilash J, Bharath SR, et al. X-ray structure of a galactose-specific lectin from Spatholobous parviflorous. Int J Biol Macromol. 2011;49(5):992-8. Published 2011 Dec 1. doi:10.1016/j.ijbiomac.2011.08.021

PMID: 21889532

5.2 Protein Sequence Databases

UniProt: P86352

5.3 3D Structure Databases

	Sl. no.	PDB ID	Method	Resolution	Access Links	3D View

AlphaFoldDB: P86352

5.4 Nucleotide Sequence Databases

No entries found in GenBank or EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR013320, IPR016363, IPR000985, IPR019825, IPR001220

PANTHER: Not found

PROSITE: PS00308, PS00307

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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