AMPDB_6951 | Pyosin cloacin_T_dom domain-containing protein

PEPTIDE SUMMARY

Pyosin cloacin_T_dom domain-containing protein

1 General Description

AMPDB ID: AMPDB_6951

Protein Names: Pyosin cloacin_T_dom domain-containing protein

Protein Family: Colicin pyosin nuclease family

Gene Name: CS537_15060

Source Organism: Yersinia mollaretii

Protein Length: 537 AA

Protein Existence: Inferred from homology

2 Protein Sequence & Composition

2.1 Sequence

MSEILHREVIYGRRELTGLGRRHRGKTSWGQGRGHRNRPKGRWVWEPIPAGTDSNNHASAEGEAIVVASNLPTEVTLSADMAVEAVKTPLVESVPKVVESARQVDETELPVDESARQIDETAEQHRITYERWVAETAERQRVENKRLVVEASKVQAEQQEAIRQNTYSLSAHPVGSLYPPGFAVAVKGAIALEPEVTQGLDASLRMALFKLSTGTAASMTGPLAVTVAAAFYPVKVSKGLHQSPCWDRPPLAGSIPLSNLGISPATGSAKQDDIELPIRMLIADADGFMEIHAVKTGVAGISAKVKVVAAQYDAHQDTYTFTTGHRLPRTFTFTPSGADISMGVPASATTPTASRHTGDVVIRHAVIHTVLPQPAWEDQDFHDYIIGFPTNSGLEPVYIYFKNPRYESGTVTGQGKTMSGLWFAGAARGLGAAIPTAIADQLRGRRFSTFDKFSEAFWAVVGHDPELSRQFKRHNISLMEKKFSPLAPASEQINGRDKFECHHVNTMKEGGAVYDMDNLRIATPKRYIKIQSRNKGE

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 59, 'R': 36, 'N': 14, 'D': 24, 'C': 2, 'Q': 21, 'E': 36, 'G': 42, 'H': 18, 'I': 28, 'L': 32, 'K': 25, 'M': 11, 'F': 18, 'P': 33, 'S': 37, 'T': 38, 'W': 8, 'Y': 13, 'V': 42

Frequencies of Amino Acids

'A': 10.99%, 'R': 6.7%, 'N': 2.61%, 'D': 4.47%, 'C': 0.37%, 'Q': 3.91%, 'E': 6.7%, 'G': 7.82%, 'H': 3.35%, 'I': 5.21%, 'L': 5.96%, 'K': 4.66%, 'M': 2.05%, 'F': 3.35%, 'P': 6.15%, 'S': 6.89%, 'T': 7.08%, 'W': 1.49%, 'Y': 2.42%, 'V': 7.82%

Missing Amino Acid(s)

No Amino Acid(s) are missing in this protein

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

273

Hydrophilic Amino Acid(s) Count

264

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	58733.4 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	77.244	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	42.098	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.359	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.672	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	8.263	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	2.566	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.263, 0.235, 0.257 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.073	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	63370, 63495	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Hydrolase

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

No PMID found

5.2 Protein Sequence Databases

UniProt: A0A0U1I9L8

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A0U1I9L8

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	PEHO01000012	GenBank \|\| EMBL

CCDS: Not found

RefSeq: WP_049648126.1

5.5 Protein-Protein Interaction Databases

STRING: 33060.ERS008532_03457

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR037146, IPR044925, IPR003615, IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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