AMPDB_631 | Wheatwin-2

PEPTIDE SUMMARY

Wheatwin-2

1 General Description

AMPDB ID: AMPDB_631

Protein Names: Wheatwin-2 (Pathogenesis-related protein 4b)

Protein Family: Nil

Gene Name: PR4B

Source Organism: Triticum aestivum (Wheat)

Protein Length: 148 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MTMAARLMLVAALLCAAAAAATAQQATNVRATYHYYRPAQNNWDLGAPAVSAYCATWDASKPLSWRSKYGWTAFCGPAGAHGQAACGKCLRVTNPATGAQITARIVDQCANGGLDLDWDTVFTKIDTNGIGYQQGHLNVNYQFVDCRD

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 28, 'R': 7, 'N': 8, 'D': 9, 'C': 7, 'Q': 9, 'E': 0, 'G': 12, 'H': 3, 'I': 4, 'L': 10, 'K': 4, 'M': 3, 'F': 3, 'P': 5, 'S': 4, 'T': 12, 'W': 5, 'Y': 7, 'V': 8

Frequencies of Amino Acids

'A': 18.92%, 'R': 4.73%, 'N': 5.41%, 'D': 6.08%, 'C': 4.73%, 'Q': 6.08%, 'E': 0%, 'G': 8.11%, 'H': 2.03%, 'I': 2.7%, 'L': 6.76%, 'K': 2.7%, 'M': 2.03%, 'F': 2.03%, 'P': 3.38%, 'S': 2.7%, 'T': 8.11%, 'W': 3.38%, 'Y': 4.73%, 'V': 5.41%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

F, H, M

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	15866.9 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	71.487	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	13.505	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.095	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.612	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	8.04	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	1.834	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.25, 0.196, 0.277 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.101	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	37930, 38305	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

B.cinerea, F.culmorum, F.graminearum

4.2 Antimicrobial Activity

Antimicrobial, Fungicide, Plant defense

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Caruso C, Bertini L, Tucci M, et al. Isolation and characterisation of wheat cDNA clones encoding PR4 proteins. DNA Seq. 1999;10(4-5):301-7. Published 1999. doi:10.3109/10425179909033956

PMID: 10727084

Citation 2: Caruso C, Caporale C, Chilosi G, et al. Structural and antifungal properties of a pathogenesis-related protein from wheat kernel. J Protein Chem. 1996;15(1):35-44. Published 1996 Jan. doi:10.1007/BF01886809

PMID: 8838588

5.2 Protein Sequence Databases

UniProt: O64393

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: O64393

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	AJ006099	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: 4565.Traes_3B_F0BA991CF.1

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR018226, IPR001153, IPR044301, IPR036908

PANTHER: PTHR46351

PROSITE: PS00771, PS00772, PS51174

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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