AMPDB_6117 | Colicin

PEPTIDE SUMMARY

Colicin

1 General Description

AMPDB ID: AMPDB_6117

Protein Names: Colicin

Protein Family: Colicin pyosin nuclease family

Gene Name: Y11_33511

Source Organism: Yersinia enterocolitica subsp. palearctica serotype O:3 (strain DSM 13030 CIP 106945 Y11)

Protein Length: 904 AA

Protein Existence: Inferred from homology

2 Protein Sequence & Composition

2.1 Sequence

MGEGHSNVSGHGSRGPTGGVKGGATGFGGGNPNSGNGWGVSQTPYGPIHNYNPSKFGHGSQGGGNRGGNRGNKATAANLAQNPELQAYMAVGGMPAVITLMDGSWGVTLSRLPAVAAYVEGHLARVGSWLMRSSPVGVAVLGMMPSSIAPDPPMGQFFTTPTLPADRVTNIPKETLKTVTDVAVNIRVRDVTEDGVQKAFLIKAPIAIQQVPVIKAVTTTRPSVFIAAVPGITPIHIRVTDTITPIDVSAVKQLAVKPNINPIENADFKEVNSSVGRNTHDAIIVFPDSTDIEPLYLSVIRITNNDELMQEARSTYEIARSEREAAERDVAKPIHSVLGALKLKKTLLEKQVTETVVHITLLESNITLLKQAEAQQWQQREALRWHNGRQTCMHKNKRRELEVSALAKQGEVNTLNQGIAELKAKYETLLMLQRDLDVVKAAEQKRIEDIRLAAEAAERQRVEDARLAAERQRIENTRLMAKIEQKFVEFEQWVAEVREMQRIKDAFRAAGGAESQNKRPIAEAVSNIDKQSAIISRNTFFFPAHPIGSLPLPGFAAGGMGSVTLIPQVAAQLSASLRRVSRRFRKFDTTLSANPLVVIIGAGSSLADDGAVSEQPLLAGSFPLSDIGLSLGTRLSWQAEVDSPVRILMASNDGRTSVYAVKTDTVNVATKVKTGEAQFDKSKGVYIFTSDSQPPRTFIFTPAQPPGLETGSILPPPASVPVFPQHTGTDIQFVAVKPDMIFLAPEESDFHDYIIWFPADSGLEPVYVYLKTSRDVPGIVTGHGQRISGIWLAEAGKGQGAPIPAQIANKLRGRKFSNFDRFREAFWQEVANDPELSGQFKFGNLGNIKNGKAPSPRESEQVGSRVKYELHHVKPISKDGAVYDIDNIRVLTPKKHIEIHKEVK

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 87, 'R': 54, 'N': 39, 'D': 40, 'C': 1, 'Q': 43, 'E': 54, 'G': 75, 'H': 19, 'I': 60, 'L': 62, 'K': 50, 'M': 16, 'F': 33, 'P': 59, 'S': 60, 'T': 53, 'W': 10, 'Y': 14, 'V': 75

Frequencies of Amino Acids

'A': 9.62%, 'R': 5.97%, 'N': 4.31%, 'D': 4.42%, 'C': 0.11%, 'Q': 4.76%, 'E': 5.97%, 'G': 8.3%, 'H': 2.1%, 'I': 6.64%, 'L': 6.86%, 'K': 5.53%, 'M': 1.77%, 'F': 3.65%, 'P': 6.53%, 'S': 6.64%, 'T': 5.86%, 'W': 1.11%, 'Y': 1.55%, 'V': 8.3%

Missing Amino Acid(s)

No Amino Acid(s) are missing in this protein

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

477

Hydrophilic Amino Acid(s) Count

427

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

123

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	98223.9 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	86.316	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	44.377	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.275	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	1.059	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	9.726	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	11.75	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.281, 0.258, 0.242 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.063	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	75860, 75860	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Hydrolase

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Batzilla J, HÃ¶per D, Antonenka U, et al. Complete genome sequence of Yersinia enterocolitica subsp. palearctica serogroup O:3. J Bacteriol. 2011;193(8):2067. Published 2011 Apr. doi:10.1128/JB.01484-10

PMID: 21296963

5.2 Protein Sequence Databases

UniProt: A0A0H3NX39

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A0H3NX39

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	FR729477	GenBank \|\| EMBL

CCDS: Not found

RefSeq: WP_005162678.1

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR024575, IPR037146, IPR044925, IPR003615, IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: yey:Y11_33511

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

Download