AMPDB_604 | Antibacterial factor-related peptide 2

PEPTIDE SUMMARY

Antibacterial factor-related peptide 2

1 General Description

AMPDB ID: AMPDB_604

Protein Names: Antibacterial factor-related peptide 2

Protein Family: Nil

Gene Name: abf-2 C50F2.10

Source Organism: Caenorhabditis elegans

Protein Length: 85 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MFVRSLFLALLLATIVAADIDFSTCARMDVPILKKAAQGLCITSCSMQNCGTGSCKKRSGRPTCVCYRCANGGGDIPLGALIKRG

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 9, 'R': 6, 'N': 2, 'D': 4, 'C': 8, 'Q': 2, 'E': 0, 'G': 9, 'H': 0, 'I': 6, 'L': 9, 'K': 5, 'M': 3, 'F': 3, 'P': 3, 'S': 6, 'T': 5, 'W': 0, 'Y': 1, 'V': 4

Frequencies of Amino Acids

'A': 10.59%, 'R': 7.06%, 'N': 2.35%, 'D': 4.71%, 'C': 9.41%, 'Q': 2.35%, 'E': 0%, 'G': 10.59%, 'H': 0%, 'I': 7.06%, 'L': 10.59%, 'K': 5.88%, 'M': 3.53%, 'F': 3.53%, 'P': 3.53%, 'S': 7.06%, 'T': 5.88%, 'W': 0%, 'Y': 1.18%, 'V': 4.71%

Missing Amino Acid(s)

E, H, W

Most Occurring Amino Acid(s)

A, G, L

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	8930.67 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	93.059	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	30.177	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.421	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.53	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	9.013	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	6.502	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.271, 0.235, 0.247 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.047	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	1490, 1990	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

A.tumefaciens (Gram-negative), B.bacteriovorus (Gram-negative), B.subtilis (Gram-positive), K.pneumoniae (Gram-negative), K.thermotolerans, K.varians (Gram-positive), S.aureus (Gram-positive), T.delbrueckii

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Fungicide, Anti-gram-negative, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Kato Y, Aizawa T, Hoshino H, et al. abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans. Biochem J. 2002;361(Pt 2):221-30. Published 2002 Jan 15. doi:10.1042/0264-6021:3610221

PMID: 11772394

Citation 2: C. elegans Sequencing Consortium. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science. 1998;282(5396):2012-8. Published 1998 Dec 11. doi:10.1126/science.282.5396.2012

PMID: 9851916

5.2 Protein Sequence Databases

UniProt: G5EC68

5.3 3D Structure Databases

	Sl. no.	PDB ID	Method	Resolution	Access Links	3D View

AlphaFoldDB: G5EC68

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	AB029810	GenBank \|\| EMBL
2.	AB029811	GenBank \|\| EMBL
3.	FO080915	GenBank \|\| EMBL

CCDS: Not found

RefSeq: NP_491252.1

5.5 Protein-Protein Interaction Databases

STRING: 6239.C50F2.10

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR031770, IPR038204

PANTHER: PTHR37971

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: ENSGT00970000196640

KEGG: cel:CELE_C50F2.10

5.9 Phylogenomic Databases

GeneTree: ENSGT00970000196640

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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