AMPDB_57847 | Colicin D-157 activity protein
PEPTIDE SUMMARY
Colicin D-157 activity protein
1 General Description
AMPDB ID: AMPDB_57847
Protein Names: Colicin D-157 activity protein
Protein Family: Nil
Gene Name: cda
Source Organism: Escherichia coli
Protein Length: 697 AA
Protein Existence: Predicted
2 Protein Sequence & Composition
2.1 Sequence
MSDYEGSGPTEGIDYGHSMVVWPSTGLISGGDVKPGGSSGIAPSMPPGWGDYSPQGIALVQSVLFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAARTVLENGLRGGLPEPSRPAAVSFARLEPASGNEQKIIRLMVTQQLEQVTDIPASQLPAAGNNVPVKYRLMDLMQNGTQYMAIIGGIPMTVPVVDAVPVPDRSRPGTNIKDVYSAPVSPNLPDLVLSVGQMNTPVLSNPEIQEEGVIAETGNYVEAGYTMSSNNHDVIVRFPDGSGVSPLYISTVEILDSNVLSQRQEAENKAKDDFRVKKEEAVARAEAEKAKAELFSKAGVNQPPVYTQEMMERANSVMNEQGALVLNNTASSVQLAMTGTGVWTAAGDIAGNISKFFSNALEKVTIPEVSPLLMRISLGALWFHSEEAGAGSDIVPGRNLEAMFSLSAQMLAGQGVVIEPGATSVNLPVRGQLINSNGQLALDLLKTGNESIPAAVPVLNAVRDTATGLDKITLPAVVGAPSRTILVNPVPQPSVPTDTGNHQPVPVTPVHTGTEVKPVEMPVTTITPVSDVGGLRDFIYWRPDAAGTGVEAVYVMLNDPLDSGRFSRKQLDKKYKHAGDFGISDTKKNRETLTKFRDAIEEHLSDKDTVEKGTYRREKGSKVYFNPNTMNVVIIKSNGEFLSGWKINPDADNGRIYLETGEL
FASTA format
2.2 Composition
Counts of Amino Acids
'A': 53, 'R': 29, 'N': 38, 'D': 36, 'C': 0, 'Q': 24, 'E': 45, 'G': 65, 'H': 8, 'I': 38, 'L': 52, 'K': 31, 'M': 20, 'F': 15, 'P': 53, 'S': 56, 'T': 40, 'W': 9, 'Y': 16, 'V': 69
Frequencies of Amino Acids
'A': 7.6%, 'R': 4.16%, 'N': 5.45%, 'D': 5.16%, 'C': 0%, 'Q': 3.44%, 'E': 6.46%, 'G': 9.33%, 'H': 1.15%, 'I': 5.45%, 'L': 7.46%, 'K': 4.45%, 'M': 2.87%, 'F': 2.15%, 'P': 7.6%, 'S': 8.03%, 'T': 5.74%, 'W': 1.29%, 'Y': 2.3%, 'V': 9.9%
Missing Amino Acid(s)
C
Most Occurring Amino Acid(s)
V
Less Occurring Amino Acid(s)
H
Hydrophobic Amino Acid(s) Count
374
Hydrophilic Amino Acid(s) Count
323
Basic Amino Acid(s) Count
81
Acidic Amino Acid(s) Count
68
Modified Amino Acid(s) Count
0
Modified Amino Acid(s) Frequencies
0
Computed by biopython (version 1.79) & proteinAnalysis (version 1)
3 Physicochemical Properties
Sl. No. Properties Values Reference
1. Molecular Mass 74668.5 Da Computed by ProtParam module (biopython 1.79)
2. Aliphatic Index 86.671 Computed by ProtParam module (biopython 1.79)
3. Instability Index (Half Life) 36.187 Computed by ProtParam module (biopython 1.79)
4. Hydrophobicity (GRAVY) -0.224 Computed by ProtParam module (biopython 1.79)
5. Hydrophobic Moment 0.643 Computed by ProtParam module (biopython 1.79)
6. Isoelectric Point 4.735 Computed by ProtParam module (biopython 1.79)
7. Charge (at pH 7) -20.202 Computed by ProtParam module (biopython 1.79)
8. Secondary Structure Fraction 0.286, 0.304, 0.244 [Helix, Turn, Sheet] Computed by ProtParam module (biopython 1.79)
9. Aromaticity 0.057 Computed by ProtParam module (biopython 1.79)
10. Molar Extinction Coefficient (cysteine|cystine) 73340, 73340 Computed by ProtParam module (biopython 1.79)
4 Activity Details
4.1 Target Organism(s)
E.coli (Gram-negative)
4.2 Antimicrobial Activity
Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative
4.3 Enzymatic Activity
Not found
4.4 Inhibitory Effect
Not found
4.5 Other Biological Activity
Non-hemolytic, Non-ribosomal
Activity data manually curated from Literature and UniProt
5 Database Cross-references
5.1 Literature Database
5.1.1 PubMed
Citation 1: Hofinger C, Karch H, Schmidt H, et al. Structure and function of plasmid pColD157 of enterohemorrhagic Escherichia coli O157 and its distribution among strains from patients with diarrhea and hemolytic-uremic syndrome. J Clin Microbiol. 1998;36(1):24-9. Published 1998 Jan. doi:10.1128/JCM.36.1.24-29.1998
PMID: 9431914
5.2 Protein Sequence Databases
UniProt: O52989
5.3 3D Structure Databases
No PDB Ids found
AlphaFoldDB: O52989
5.4 Nucleotide Sequence Databases
Sl. no. Accession(s) Access Link(s)
1. Y10412 GenBank || EMBL
CCDS: Not found
RefSeq: Not found
5.5 Protein-Protein Interaction Databases
STRING: Not found
IntAct: Not found
MINT: Not found
DIP: Not found
BioGRID: Not found
5.6 Ligand Databases
BindingDB: Not found
DrugBank: Not found
ChEMBL: Not found
5.7 Family & Domain Databases
PANTHER: Not found
PROSITE: Not found
5.8 Genome Annotation Databases
Ensembl: Not found
KEGG: Not found
5.9 Phylogenomic Databases
GeneTree: Not found
5.10 Enzyme & Pathway Databases
BRENDA: Not found
BioCyc: Not found
5.11 Protein-RNA Interaction Databases
RNAct: Not found




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