AMPDB_575 | Bacteriocin glycocin F
PEPTIDE SUMMARY
Bacteriocin glycocin F
1 General Description
AMPDB ID: AMPDB_575
Protein Names: Bacteriocin glycocin F (GccF)
Protein Family: Nil
Gene Name: gccF
Protein Length: 64 AA
Protein Existence: Evidence at protein level
2 Protein Sequence & Composition
2.1 Sequence
MSKLVKTLTISEISKAQNNGGKPAWCWYTLAMCGAGYDSGTCDYMYSHCFGIKHHSSGSSSYHC
FASTA format
2.2 Composition
Counts of Amino Acids
'A': 4, 'R': 0, 'N': 2, 'D': 2, 'C': 5, 'Q': 1, 'E': 1, 'G': 7, 'H': 4, 'I': 3, 'L': 3, 'K': 5, 'M': 3, 'F': 1, 'P': 1, 'S': 10, 'T': 4, 'W': 2, 'Y': 5, 'V': 1
Frequencies of Amino Acids
'A': 6.25%, 'R': 0%, 'N': 3.13%, 'D': 3.13%, 'C': 7.81%, 'Q': 1.56%, 'E': 1.56%, 'G': 10.94%, 'H': 6.25%, 'I': 4.69%, 'L': 4.69%, 'K': 7.81%, 'M': 4.69%, 'F': 1.56%, 'P': 1.56%, 'S': 15.63%, 'T': 6.25%, 'W': 3.13%, 'Y': 7.81%, 'V': 1.56%
Missing Amino Acid(s)
R
Most Occurring Amino Acid(s)
S
Less Occurring Amino Acid(s)
E, F, P, Q, V
Hydrophobic Amino Acid(s) Count
25
Hydrophilic Amino Acid(s) Count
39
Basic Amino Acid(s) Count
3
Acidic Amino Acid(s) Count
9
Modified Amino Acid(s) Count
0
Modified Amino Acid(s) Frequencies
0
Computed by biopython (version 1.79) & proteinAnalysis (version 1)
3 Physicochemical Properties
Sl. No. Properties Values Reference
1. Molecular Mass 7001.92 Da Computed by ProtParam module (biopython 1.79)
2. Aliphatic Index 47.344 Computed by ProtParam module (biopython 1.79)
3. Instability Index (Half Life) 48.017 Computed by ProtParam module (biopython 1.79)
4. Hydrophobicity (GRAVY) -0.305 Computed by ProtParam module (biopython 1.79)
5. Hydrophobic Moment 0.514 Computed by ProtParam module (biopython 1.79)
6. Isoelectric Point 8.215 Computed by ProtParam module (biopython 1.79)
7. Charge (at pH 7) 2.049 Computed by ProtParam module (biopython 1.79)
8. Secondary Structure Fraction 0.234, 0.313, 0.172 [Helix, Turn, Sheet] Computed by ProtParam module (biopython 1.79)
9. Aromaticity 0.125 Computed by ProtParam module (biopython 1.79)
10. Molar Extinction Coefficient (cysteine|cystine) 18450, 18700 Computed by ProtParam module (biopython 1.79)
4 Activity Details
4.1 Target Organism(s)
L.plantarum (Gram-positive)
4.2 Antimicrobial Activity
Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-Positive
4.3 Enzymatic Activity
Not found
4.4 Inhibitory Effect
Not found
4.5 Other Biological Activity
Non-hemolytic, Non-ribosomal
Activity data manually curated from Literature and UniProt
5 Database Cross-references
5.1 Literature Database
5.1.1 PubMed
Citation 1: Stepper J, Shastri S, Loo TS, et al. Cysteine S-glycosylation, a new post-translational modification found in glycopeptide bacteriocins. FEBS Lett. 2011;585(4):645-50. Published 2011 Feb 18. doi:10.1016/j.febslet.2011.01.023
PMID: 21251913
Citation 2: Venugopal H, Edwards PJ, Schwalbe M, et al. Structural, dynamic, and chemical characterization of a novel S-glycosylated bacteriocin. Biochemistry. 2011;50(14):2748-55. Published 2011 Apr 12. doi:10.1021/bi200217u
PMID: 21395300
5.2 Protein Sequence Databases
UniProt: E9K9Z1
5.3 3D Structure Databases
Sl. no. PDB ID Method Resolution Access Links 3D View
AlphaFoldDB: E9K9Z1
5.4 Nucleotide Sequence Databases
Sl. no. Accession(s) Access Link(s)
1. GU552553 GenBank || EMBL
CCDS: Not found
RefSeq: Not found
5.5 Protein-Protein Interaction Databases
STRING: Not found
IntAct: Not found
MINT: Not found
DIP: Not found
BioGRID: Not found
5.6 Ligand Databases
BindingDB: Not found
DrugBank: Not found
ChEMBL: Not found
5.7 Family & Domain Databases
InterPro: Not found
PANTHER: Not found
PROSITE: Not found
5.8 Genome Annotation Databases
Ensembl: Not found
KEGG: Not found
5.9 Phylogenomic Databases
GeneTree: Not found
5.10 Enzyme & Pathway Databases
BRENDA: Not found
BioCyc: Not found
5.11 Protein-RNA Interaction Databases
RNAct: Not found




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