AMPDB_57 | Oxyopinin-4a

PEPTIDE SUMMARY

Oxyopinin-4a

1 General Description

AMPDB ID: AMPDB_57

Protein Names: Oxyopinin-4a (Oxt-4a)

Protein Family: Nil

Gene Name: Nil

Source Organism: Oxyopes takobius (Lynx spider) (Oxyopes foliiformis)

Protein Length: 77 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MKISQVFIFVFLLMISVAWANEAYEEESNYLSERFDADVEEITPEFRGIRCPKSWKCKAFKQRVLKRLLAMLRQHAF

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 7, 'R': 6, 'N': 2, 'D': 2, 'C': 2, 'Q': 3, 'E': 8, 'G': 1, 'H': 1, 'I': 5, 'L': 7, 'K': 6, 'M': 3, 'F': 7, 'P': 2, 'S': 5, 'T': 1, 'W': 2, 'Y': 2, 'V': 5

Frequencies of Amino Acids

'A': 9.09%, 'R': 7.79%, 'N': 2.6%, 'D': 2.6%, 'C': 2.6%, 'Q': 3.9%, 'E': 10.39%, 'G': 1.3%, 'H': 1.3%, 'I': 6.49%, 'L': 9.09%, 'K': 7.79%, 'M': 3.9%, 'F': 9.09%, 'P': 2.6%, 'S': 6.49%, 'T': 1.3%, 'W': 2.6%, 'Y': 2.6%, 'V': 6.49%

Missing Amino Acid(s)

No Amino Acid(s) are missing in this protein

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

G, H, T

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	9204.81 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	88.701	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	39.874	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.075	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.825	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	8.75	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	1.977	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.364, 0.13, 0.325 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.143	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	13980, 14105	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

B.subtilis (Gram-positive), E.coli (Gram-negative), P.fluorescens (Gram-negative), S.aureus (Gram-positive)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Anti-gram-negative, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Cytolysis, Toxin, Hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Dubovskii PV, Vassilevski AA, Samsonova OV, et al. Novel lynx spider toxin shares common molecular architecture with defense peptides from frog skin. FEBS J. 2011;278(22):4382-93. Published 2011 Nov. doi:10.1111/j.1742-4658.2011.08361.x

PMID: 21933345

5.2 Protein Sequence Databases

UniProt: F8J4S0

5.3 3D Structure Databases

	Sl. no.	PDB ID	Method	Resolution	Access Links	3D View

AlphaFoldDB: F8J4S0

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	FN997582	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: Not found

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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