AMPDB_56672 | Carocin S2K

PEPTIDE SUMMARY

Carocin S2K

1 General Description

AMPDB ID: AMPDB_56672

Protein Names: Carocin S2K

Protein Family: Nil

Gene Name: Nil

Source Organism: Pectobacterium carotovorum subsp. carotovorum (Erwinia carotovora subsp. carotovora)

Protein Length: 783 AA

Protein Existence: Predicted

2 Protein Sequence & Composition

2.1 Sequence

MIKYRLYAPNDGDTMTVDGGGGWDSPVNDDRKGGNDRDDGKGGSAVDFSKNPEKQAIVNPYLAIALPMPVYPIFGTPGFTINTIAIETGLAKISAVISSALPVAGRLLGVTVGAMWPSSTAPSSLDSIYNQAHQQALAQLAAQQGVLNKGYNVTAMPAGFVSSLPVSEIKSLPTAPASLLAQSVVNTELSQRQLALTQPTTNVPVANIPVVKAEKTAVPGVYSAKIIAGEPAFQIKVDSTKPALAQNPPKVKDDVQVSSFLSTPVADTHHAFIDFGSDHEPVYVSLSKIVTAEEEKKQVAEAKRREQEWLLRHPITAAERKLTEIHQVISFAQQLKESSAATISGKTKTVAVYQEQVNTAAKNRDNFYNQNRGLLSAGITGGPGYPIYLALWQTMNNFHQAYFRANNALEQESHVLNQARSDLAKAEQLLAENNLLQVETERTLAEEKEIKRNRVNVSTFGTVQTQLSTLLSAFYAATFGSTTSISQSVPSGALASFSYKSQGMIGSGKIVGKDVDILFSIPVKDIPGYKSPTNLDDLAKKNGSLDLPIRLAFSDENGERVLRAFKAGSLRVPSSVRGVAGSYDKNTGIFSAKIDGVSSRLVLENPAFPPTGNVGNTGNTAPDYKALLNTGIDVKPVDKITVTVTPVAEPMEFDDYIIWTPTADGSGVEPIYVVFNDPLDSDRFTRKQLDKKYLKHAKDFGIVDTRKNSETLTKFRDAIITHLEEKETFEKGTYLLVKDSKVFFNPKTNNVVVMDKDNKFISGWKLDVDSQQYKNYVNNGVLR

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 72, 'R': 27, 'N': 45, 'D': 46, 'C': 0, 'Q': 35, 'E': 37, 'G': 53, 'H': 10, 'I': 42, 'L': 62, 'K': 56, 'M': 9, 'F': 30, 'P': 45, 'S': 62, 'T': 55, 'W': 6, 'Y': 24, 'V': 67

Frequencies of Amino Acids

'A': 9.2%, 'R': 3.45%, 'N': 5.75%, 'D': 5.87%, 'C': 0%, 'Q': 4.47%, 'E': 4.73%, 'G': 6.77%, 'H': 1.28%, 'I': 5.36%, 'L': 7.92%, 'K': 7.15%, 'M': 1.15%, 'F': 3.83%, 'P': 5.75%, 'S': 7.92%, 'T': 7.02%, 'W': 0.77%, 'Y': 3.07%, 'V': 8.56%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

386

Hydrophilic Amino Acid(s) Count

397

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	84986.1 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	85.811	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	31.158	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.286	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.771	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	7.903	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	0.956	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.295, 0.262, 0.23 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.077	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	68760, 68760	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Chan YC, Wu JL, Wu HP, et al. Cloning, purification, and functional characterization of Carocin S2, a ribonuclease bacteriocin produced by Pectobacterium carotovorum. BMC Microbiol. 2011;11:99. Published 2011 May 12. doi:10.1186/1471-2180-11-99

PMID: 21569432

5.2 Protein Sequence Databases

UniProt: F8R4N7

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: F8R4N7

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	HM475143	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR038233, IPR024440, IPR037178, IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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