AMPDB_560 | Venom peptide 3

PEPTIDE SUMMARY

Venom peptide 3

1 General Description

AMPDB ID: AMPDB_560

Protein Names: Venom peptide 3 (OdVP3)

Protein Family: MCD family

Gene Name: VP3

Source Organism: Orancistrocerus drewseni (Solitary wasp)

Protein Length: 68 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MTKQSIVIVLFAAIAMMACLQRVTAEPAPEPIAAPIAEPYANPEAIASPEAKDLHTVVSAILQALGKK

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 15, 'R': 1, 'N': 1, 'D': 1, 'C': 1, 'Q': 3, 'E': 5, 'G': 1, 'H': 1, 'I': 7, 'L': 5, 'K': 4, 'M': 3, 'F': 1, 'P': 7, 'S': 3, 'T': 3, 'W': 0, 'Y': 1, 'V': 5

Frequencies of Amino Acids

'A': 22.06%, 'R': 1.47%, 'N': 1.47%, 'D': 1.47%, 'C': 1.47%, 'Q': 4.41%, 'E': 7.35%, 'G': 1.47%, 'H': 1.47%, 'I': 10.29%, 'L': 7.35%, 'K': 5.88%, 'M': 4.41%, 'F': 1.47%, 'P': 10.29%, 'S': 4.41%, 'T': 4.41%, 'W': 0%, 'Y': 1.47%, 'V': 7.35%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

C, D, F, G, H, N, R, Y

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	7111.45 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	112.206	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	70.559	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.497	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.51	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	5.71	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-0.966	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.279, 0.176, 0.412 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.029	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	1490, 1490	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

B.cinerea, C.albicans, E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Fungicide, Anti-candida, Anti-gram-negative

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Toxin, Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Baek JH, Lee SH, Lee SH. Isolation and molecular cloning of venom peptides from Orancistrocerus drewseni (Hymenoptera: Eumenidae). Toxicon. 2010;55(4):711-8. Published 2010 Apr 1. doi:10.1016/j.toxicon.2009.10.023

PMID: 19857508

5.2 Protein Sequence Databases

UniProt: C7DT09

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: C7DT09

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	GQ205582	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: Not found

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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