AMPDB_55815 | Disrupted colicin B activity protein

PEPTIDE SUMMARY

Disrupted colicin B activity protein

1 General Description

AMPDB ID: AMPDB_55815

Protein Names: Disrupted colicin B activity protein

Protein Family: Nil

Gene Name: cba

Source Organism: Escherichia coli

Protein Length: 186 AA

Protein Existence: Predicted

2 Protein Sequence & Composition

2.1 Sequence

MSDNEGSVPTEGIDYGDTMVVWPSTGRIPGGDVKPGGSSGLAPSMPPGWGDYSPQGIALVQSVLFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAARTVLENGLRGGLPEPSRPAAVSFARLEPASGNEQKIIRLMVTQQLEQVTDIPASQLPAAGNNVPVKYRLTDLMQNIWLLSEVFR

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 11, 'R': 10, 'N': 7, 'D': 9, 'C': 0, 'Q': 8, 'E': 12, 'G': 21, 'H': 1, 'I': 11, 'L': 16, 'K': 5, 'M': 5, 'F': 3, 'P': 17, 'S': 18, 'T': 7, 'W': 6, 'Y': 3, 'V': 16

Frequencies of Amino Acids

'A': 5.91%, 'R': 5.38%, 'N': 3.76%, 'D': 4.84%, 'C': 0%, 'Q': 4.3%, 'E': 6.45%, 'G': 11.29%, 'H': 0.54%, 'I': 5.91%, 'L': 8.6%, 'K': 2.69%, 'M': 2.69%, 'F': 1.61%, 'P': 9.14%, 'S': 9.68%, 'T': 3.76%, 'W': 3.23%, 'Y': 1.61%, 'V': 8.6%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

106

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	20018.7 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	87.473	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	51.47	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.23	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.636	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	4.536	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-5.89	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.296, 0.339, 0.237 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.065	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	37470, 37470	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Christenson JK, Gordon DM, Gordon DM. Evolution of colicin BM plasmids: the loss of the colicin B activity gene. Microbiology (Reading). 2009;155(Pt 5):1645-1655. Published 2009 May. doi:10.1099/mic.0.026666-0

PMID: 19372169

5.2 Protein Sequence Databases

UniProt: C3UUK1

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: C3UUK1

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	FJ664730	GenBank \|\| EMBL
2.	FJ664731	GenBank \|\| EMBL
3.	FJ664732	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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