AMPDB_544 | Lysozyme C

PEPTIDE SUMMARY

Lysozyme C

1 General Description

AMPDB ID: AMPDB_544

Protein Names: Lysozyme C (EC 3.2.1.17) (1;4-beta-N-acetylmuramidase C)

Protein Family: Glycosyl hydrolase 22 family

Gene Name: Nil

Source Organism: Penaeus merguiensis (Banana prawn) (Fenneropenaeus merguiensis)

Protein Length: 158 AA

Protein Existence: Evidence at transcript level

2 Protein Sequence & Composition

2.1 Sequence

MRVLPLALLVGLLAVSDAKVLGKCEFARLLETRYNLSRNDIKNWVCIAEFESSFNTAATNRNRNRSTDYGIFQINNKYWCGSDYGKNVCGIPCSDLMSDDITAALRCAETVRRATERYRGRGKGYTAWVAYNSKCKKRDLDQYMAECWSRGSNSIFPF

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 14, 'R': 15, 'N': 12, 'D': 9, 'C': 8, 'Q': 2, 'E': 7, 'G': 10, 'H': 0, 'I': 7, 'L': 13, 'K': 9, 'M': 3, 'F': 6, 'P': 3, 'S': 12, 'T': 8, 'W': 4, 'Y': 8, 'V': 8

Frequencies of Amino Acids

'A': 8.86%, 'R': 9.49%, 'N': 7.59%, 'D': 5.7%, 'C': 5.06%, 'Q': 1.27%, 'E': 4.43%, 'G': 6.33%, 'H': 0%, 'I': 4.43%, 'L': 8.23%, 'K': 5.7%, 'M': 1.9%, 'F': 3.8%, 'P': 1.9%, 'S': 7.59%, 'T': 5.06%, 'W': 2.53%, 'Y': 5.06%, 'V': 5.06%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	17998.5 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	72.911	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	27.73	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.401	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.724	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	9.088	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	7.509	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.291, 0.234, 0.234 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.114	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	33920, 34420	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

M.luteus (Gram-negative), V.alginolyticus (Gram-negative), V.parahaemolyticus (Gram-negative)

4.2 Antimicrobial Activity

Antimicrobial, Bacteriolytic enzyme, Anti-gram-negative

4.3 Enzymatic Activity

Glycosidase, Hydrolase

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Mai WJ, Hu CQ, Hu CQ. Molecular cloning, characterization, expression and antibacterial analysis of a lysozyme homologue from Fenneropenaeus merguiensis. Mol Biol Rep. 2009;36(6):1587-95. Published 2009 Jul. doi:10.1007/s11033-008-9355-8

PMID: 18798009

5.2 Protein Sequence Databases

UniProt: C1IIX1

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: C1IIX1

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	EU591712	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR001916, IPR019799, IPR023346

PANTHER: PTHR11407

PROSITE: PS00128, PS51348

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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