AMPDB_48809 | Pyocin-S1

PEPTIDE SUMMARY

Pyocin-S1

1 General Description

AMPDB ID: AMPDB_48809

Protein Names: Pyocin-S1 (EC 3.1.-.-)

Protein Family: Colicin pyosin nuclease family

Gene Name: pys1 SB00610_04012

Source Organism: Klebsiella quasipneumoniae subsp. similipneumoniae

Protein Length: 288 AA

Protein Existence: Inferred from homology

2 Protein Sequence & Composition

2.1 Sequence

MMPGDAFGLPDTAALNKAADQKTSVSMPVRGRLVMNDSGILDVQLVKTNTAGAVKVARAVLDKETGYWGYTLPAVADVPAQTIFVSPADAPGANGPLTLSGPVPLPERILHTGDQISAPQATDKTVTPVADDLDFEDIILVFPPESGLKPLYMMYRSPRNMPGTVSGKGQNVGNNWMGGASTGDGAPVPSQIADKLRGKTFGSFDSFRRAFWKAVADDSALSKQFSEADINQMKAGRAPTADFLESVGKRVKIELHHEKEISQGGAVMDVDNIKALTPKNHIETHKGK

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 31, 'R': 11, 'N': 11, 'D': 23, 'C': 0, 'Q': 10, 'E': 10, 'G': 27, 'H': 5, 'I': 12, 'L': 20, 'K': 20, 'M': 10, 'F': 10, 'P': 22, 'S': 18, 'T': 18, 'W': 3, 'Y': 4, 'V': 23

Frequencies of Amino Acids

'A': 10.76%, 'R': 3.82%, 'N': 3.82%, 'D': 7.99%, 'C': 0%, 'Q': 3.47%, 'E': 3.47%, 'G': 9.38%, 'H': 1.74%, 'I': 4.17%, 'L': 6.94%, 'K': 6.94%, 'M': 3.47%, 'F': 3.47%, 'P': 7.64%, 'S': 6.25%, 'T': 6.25%, 'W': 1.04%, 'Y': 1.39%, 'V': 7.99%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

158

Hydrophilic Amino Acid(s) Count

130

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	30623.8 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	77.257	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	42.005	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.292	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.681	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	6.693	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-1.529	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.25, 0.271, 0.247 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.059	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	22460, 22460	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Hydrolase

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

No PMID found

5.2 Protein Sequence Databases

UniProt: A0A663BLV5

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A663BLV5

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	CAAHGG010000142	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR037146, IPR044925, IPR003615, IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

Download