AMPDB_468 | U10-myrmicitoxin-Mri1b

PEPTIDE SUMMARY

U10-myrmicitoxin-Mri1b

1 General Description

AMPDB ID: AMPDB_468

Protein Names: U10-myrmicitoxin-Mri1b (U10-MYRTX-Mri1b)

Protein Family: Formicidae venom precursor-01 superfamily

Gene Name: Nil

Source Organism: Manica rubida (European giant red ant)

Protein Length: 81 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MRLSYISLTLAIIFVMAIVHAPETEAKAYPEADAVAEAIAVGEADAVGVADPGIKDALAKIWKILKAEVPTVAAAIENKVG

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 19, 'R': 1, 'N': 1, 'D': 4, 'C': 0, 'Q': 0, 'E': 7, 'G': 4, 'H': 1, 'I': 9, 'L': 5, 'K': 6, 'M': 2, 'F': 1, 'P': 4, 'S': 2, 'T': 3, 'W': 1, 'Y': 2, 'V': 9

Frequencies of Amino Acids

'A': 23.46%, 'R': 1.23%, 'N': 1.23%, 'D': 4.94%, 'C': 0%, 'Q': 0%, 'E': 8.64%, 'G': 4.94%, 'H': 1.23%, 'I': 11.11%, 'L': 6.17%, 'K': 7.41%, 'M': 2.47%, 'F': 1.23%, 'P': 4.94%, 'S': 2.47%, 'T': 3.7%, 'W': 1.23%, 'Y': 2.47%, 'V': 11.11%

Missing Amino Acid(s)

C, Q

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

F, H, N, R, W

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	8401.85 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	123.086	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	19.586	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.615	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.652	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	4.48	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-3.9	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.333, 0.136, 0.407 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.049	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	8480, 8480	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

L.caesar

4.2 Antimicrobial Activity

Antimicrobial

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Toxin, Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Touchard A, Aili SR, TÃ©nÃ© N, et al. Venom Peptide Repertoire of the European Myrmicine Ant Manica rubida: Identification of Insecticidal Toxins. J Proteome Res. 2020;19(4):1800-1811. Published 2020 Apr 3. doi:10.1021/acs.jproteome.0c00048

PMID: 32182430

5.2 Protein Sequence Databases

UniProt: A0A6G9KJV6

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A6G9KJV6

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	MN765034	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: Not found

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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