AMPDB_4588 | Lysozyme g

PEPTIDE SUMMARY

Lysozyme g

1 General Description

AMPDB ID: AMPDB_4588

Protein Names: Lysozyme g (EC 3.2.1.17) (1;4-beta-N-acetylmuramidase)

Protein Family: Glycosyl hydrolase 23 family

Gene Name: Nil

Source Organism: Epinephelus coioides (Orange-spotted grouper) (Epinephelus nebulosus)

Protein Length: 194 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MGYGNIMNVETTGASWQTAQQDKLGYSGVRASHTMANTDSGRMERYRSKINSVGAKYGIDPALIAAIISEESRAGNVLHDGWGDYDSNRGAYNAWGLMQVDVNPNGGGHTARGAWDSEEHLSQGAEILVYFIGRIRNKFPGWNTEQQLKGGIAAYNMGDGNVHSYDNVDGRTTGGDYSNDVVARAQWYKTQKGF

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 18, 'R': 11, 'N': 15, 'D': 13, 'C': 0, 'Q': 9, 'E': 8, 'G': 28, 'H': 5, 'I': 10, 'L': 7, 'K': 7, 'M': 6, 'F': 3, 'P': 3, 'S': 13, 'T': 10, 'W': 6, 'Y': 11, 'V': 11

Frequencies of Amino Acids

'A': 9.28%, 'R': 5.67%, 'N': 7.73%, 'D': 6.7%, 'C': 0%, 'Q': 4.64%, 'E': 4.12%, 'G': 14.43%, 'H': 2.58%, 'I': 5.15%, 'L': 3.61%, 'K': 3.61%, 'M': 3.09%, 'F': 1.55%, 'P': 1.55%, 'S': 6.7%, 'T': 5.15%, 'W': 3.09%, 'Y': 5.67%, 'V': 5.67%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

F, P

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

102

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	21179.2 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	59.897	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	24.764	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.688	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.557	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	6.354	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-2.539	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.247, 0.304, 0.201 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.103	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	49390, 49390	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

A.hydrophila (Gram-negative), Epinephelus fario, P.fluorescens (Gram-negative), V.alginolyticus (Gram-negative), V.fluvialis (Gram-positive), V.parahaemolyticus (Gram-negative), V.vulnificus (Gram-negative)

4.2 Antimicrobial Activity

Antimicrobial, Bacteriolytic enzyme, Anti-gram-negative, Anti-gram-Positive

4.3 Enzymatic Activity

Glycosidase, Hydrolase

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Yin ZX, He JG, Deng WX, et al. Molecular cloning, expression of orange-spotted grouper goose-type lysozyme cDNA, and lytic activity of its recombinant protein. Dis Aquat Organ. 2003;55(2):117-23. Published 2003 Jul 8. doi:10.3354/dao055117

PMID: 12911059

5.2 Protein Sequence Databases

UniProt: Q90X99

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: Q90X99

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	AF416458	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR002152, IPR023346, IPR008258

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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