AMPDB_4556 | Bacteriocin aureocin A53

PEPTIDE SUMMARY

Bacteriocin aureocin A53

1 General Description

AMPDB ID: AMPDB_4556

Protein Names: Bacteriocin aureocin A53

Protein Family: Nil

Gene Name: aucA

Source Organism: Staphylococcus aureus

Protein Length: 51 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MSWLNFLKYIAKYGKKAVSAAWKYKGKVLEWLNVGPTLEWVWQKLKKIAGL

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 5, 'R': 0, 'N': 2, 'D': 0, 'C': 0, 'Q': 1, 'E': 2, 'G': 4, 'H': 0, 'I': 2, 'L': 7, 'K': 10, 'M': 1, 'F': 1, 'P': 1, 'S': 2, 'T': 1, 'W': 5, 'Y': 3, 'V': 4

Frequencies of Amino Acids

'A': 9.8%, 'R': 0%, 'N': 3.92%, 'D': 0%, 'C': 0%, 'Q': 1.96%, 'E': 3.92%, 'G': 7.84%, 'H': 0%, 'I': 3.92%, 'L': 13.73%, 'K': 19.61%, 'M': 1.96%, 'F': 1.96%, 'P': 1.96%, 'S': 3.92%, 'T': 1.96%, 'W': 9.8%, 'Y': 5.88%, 'V': 7.84%

Missing Amino Acid(s)

C, D, H, R

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

F, M, P, Q, T

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	5984.23 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	101.373	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	-3.894	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.084	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.722	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	10.727	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	7.996	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.431, 0.176, 0.294 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.176	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	31970, 31970	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

L.monocytogenes (Gram-positive), S.aureus (Gram-positive)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Netz DJ, Pohl R, Beck-Sickinger AG, et al. Biochemical characterisation and genetic analysis of aureocin A53, a new, atypical bacteriocin from Staphylococcus aureus. J Mol Biol. 2002;319(3):745-56. Published 2002 Jun 7. doi:10.1016/S0022-2836(02)00368-6

PMID: 12054867

5.2 Protein Sequence Databases

UniProt: Q8GPI4

5.3 3D Structure Databases

	Sl. no.	PDB ID	Method	Resolution	Access Links	3D View

AlphaFoldDB: Q8GPI4

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	AF447813	GenBank \|\| EMBL

CCDS: Not found

RefSeq: WP_032072954.1, YP_009072012.1

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR020968

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

Download