AMPDB_44485 | Uropathogenic protein

PEPTIDE SUMMARY

Uropathogenic protein

1 General Description

AMPDB ID: AMPDB_44485

Protein Names: Uropathogenic protein

Protein Family: Colicin pyosin nuclease family

Gene Name: Usp

Source Organism: Escherichia coli

Protein Length: 341 AA

Protein Existence: Inferred from homology

2 Protein Sequence & Composition

2.1 Sequence

PSSVLATQIWGKWSLSGVLSATRGSYIGALASALYIPSAGEGSARVPGRDEFWYEEELRQKALAGSTATTRVRFFWGTDIHGKPQVYGVHTGEGTPYENVRVANMQWNEQTQRYEFTPAHDVDGPLITWTPENPEHGNVPGHTGNDRPPLDQPTILVTPIPDGTDTYTTPPFPVPDPKEFNDYILVFPAGSGIKPIYVYLKEDPRKLPGVVTGRGVPLSPGTRWLDMSVSNNGNGAPIPAHIADKLRGREFKTFDEFREALWLEVSKDSVLLAQFIKSNQNNVSQGYSPYVPEEGYYYGPNEIVKKFQIHHVVAIEHGGGVYDIDNFRIVTPRLHDEIHYR

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 19, 'R': 18, 'N': 15, 'D': 18, 'C': 0, 'Q': 11, 'E': 22, 'G': 33, 'H': 11, 'I': 19, 'L': 21, 'K': 13, 'M': 2, 'F': 13, 'P': 32, 'S': 19, 'T': 23, 'W': 8, 'Y': 17, 'V': 27

Frequencies of Amino Acids

'A': 5.57%, 'R': 5.28%, 'N': 4.4%, 'D': 5.28%, 'C': 0%, 'Q': 3.23%, 'E': 6.45%, 'G': 9.68%, 'H': 3.23%, 'I': 5.57%, 'L': 6.16%, 'K': 3.81%, 'M': 0.59%, 'F': 3.81%, 'P': 9.38%, 'S': 5.57%, 'T': 6.74%, 'W': 2.35%, 'Y': 4.99%, 'V': 7.92%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

174

Hydrophilic Amino Acid(s) Count

167

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	38000.5 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	74.282	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	27.223	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.498	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.518	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	5.959	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-7.973	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.308, 0.29, 0.188 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.111	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	69330, 69330	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Hydrolase

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

No PMID found

5.2 Protein Sequence Databases

UniProt: A0A3G4QTS8

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A3G4QTS8

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	MH753071	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR037146, IPR044925, IPR003615, IPR003060, IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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