AMPDB_4428 | Scygonadin

PEPTIDE SUMMARY

Scygonadin

1 General Description

AMPDB ID: AMPDB_4428

Protein Names: Scygonadin

Protein Family: Nil

Gene Name: Nil

Source Organism: Scylla serrata (Mud crab)

Protein Length: 126 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MRSSLLLGLTVVVLLGVIVPPCMAGQALNKLMPKIVSAIIYMVGQPNAGVTFLGHQCLVESTRQPDGFYTAKMSCASWTHDNPIVGEGRSRVELEALKGSITNFVQTASNYKKFTIDEVEDWIASY

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 9, 'R': 4, 'N': 5, 'D': 4, 'C': 3, 'Q': 5, 'E': 6, 'G': 10, 'H': 2, 'I': 8, 'L': 12, 'K': 6, 'M': 5, 'F': 4, 'P': 6, 'S': 10, 'T': 8, 'W': 2, 'Y': 4, 'V': 13

Frequencies of Amino Acids

'A': 7.14%, 'R': 3.17%, 'N': 3.97%, 'D': 3.17%, 'C': 2.38%, 'Q': 3.97%, 'E': 4.76%, 'G': 7.94%, 'H': 1.59%, 'I': 6.35%, 'L': 9.52%, 'K': 4.76%, 'M': 3.97%, 'F': 3.17%, 'P': 4.76%, 'S': 7.94%, 'T': 6.35%, 'W': 1.59%, 'Y': 3.17%, 'V': 10.32%

Missing Amino Acid(s)

No Amino Acid(s) are missing in this protein

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

H, W

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	13736 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	98.968	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	42.619	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.227	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.593	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	7.342	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	0.001	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.341, 0.246, 0.254 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.079	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	16960, 17085	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

M.luteus (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Anti-gram-negative

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Wang KJ, Huang WS, Yang M, et al. A male-specific expression gene, encodes a novel anionic antimicrobial peptide, scygonadin, in Scylla serrata. Mol Immunol. 2007;44(8):1961-8. Published 2007 Mar. doi:10.1016/j.molimm.2006.09.036

PMID: 17092560

5.2 Protein Sequence Databases

UniProt: Q5D710

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: Q5D710

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	AY864802	GenBank \|\| EMBL
2.	DQ059303	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR024509, IPR038539

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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