AMPDB_4302 | Aplysianin-A

PEPTIDE SUMMARY

Aplysianin-A

1 General Description

AMPDB ID: AMPDB_4302

Protein Names: Aplysianin-A

Protein Family: Nil

Gene Name: Nil

Source Organism: Aplysia kurodai (Kuroda`s sea hare)

Protein Length: 556 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MAVRFLALGLLIFVTSCSGRRVCESQQSCDDEQCDETLNIAIVGAGPSGAYSAYKMRHSGKDVGLFEYCNRVGGRLYTYQLPNTPDVNLELGGMRYITGAHNILQEVTKELGLKSVLFTEGFGRPGRTRYFLRGQSLTHEEVQSGDVPYNLTTIEKLNQGRIYEYYLKELTGFDIGNGSISREQLLKLRVSDGRLLYQLTFDEALDLVASPEGKEFARDVHVFHTEVTSDANAVSVFDDHLGEDGAGDAILTVEEGMQKVPKELIKEFKKTSASNQVQLNKYLQAIRSKSDHSFVLYFRPTSTVDGKTTILDYRPLQRVCARQVILALPVFALRRLDWPPLHEGRAETAYAAVRNMAASKVFMTFDQAWWLDRNFTDNTAFVTKGDTPFSQMYDWKKSNVSGDYILIASYADGNNTLYQKVLRDQGESINGSEPGANRVSEPLKNNILDHLSEAYGVDRSTIPEPKTAVSQFWTDYPFGCGWITWRAGYHFDDVMSTMRRPSLKDEVYVVGADYSWGLMSSWTEGALETADAVLKDYFKGECAKPPSVDHLDSHMA

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 39, 'R': 32, 'N': 21, 'D': 39, 'C': 8, 'Q': 21, 'E': 34, 'G': 44, 'H': 12, 'I': 20, 'L': 53, 'K': 27, 'M': 11, 'F': 24, 'P': 21, 'S': 40, 'T': 35, 'W': 9, 'Y': 26, 'V': 40

Frequencies of Amino Acids

'A': 7.01%, 'R': 5.76%, 'N': 3.78%, 'D': 7.01%, 'C': 1.44%, 'Q': 3.78%, 'E': 6.12%, 'G': 7.91%, 'H': 2.16%, 'I': 3.6%, 'L': 9.53%, 'K': 4.86%, 'M': 1.98%, 'F': 4.32%, 'P': 3.78%, 'S': 7.19%, 'T': 6.29%, 'W': 1.62%, 'Y': 4.68%, 'V': 7.19%

Missing Amino Acid(s)

No Amino Acid(s) are missing in this protein

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

261

Hydrophilic Amino Acid(s) Count

295

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	62376.2 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	79.083	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	39.11	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.363	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.731	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	5.393	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-13.359	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.309, 0.227, 0.246 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.106	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	88240, 88740	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

Gram Negative Bacteria and Gram Positive Bacteria

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Anti-gram-negative, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Takamatsu N, Shiba T, Muramoto K, et al. Molecular cloning of the defense factor in the albumen gland of the sea hare Aplysia kurodai. FEBS Lett. 1995;377(3):373-6. Published 1995 Dec 27. doi:10.1016/0014-5793(95)01375-X

PMID: 8549758

5.2 Protein Sequence Databases

UniProt: Q17043

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: Q17043

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	D83255	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR002937, IPR036188

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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