AMPDB_4232 | Osmotin

PEPTIDE SUMMARY

Osmotin

1 General Description

AMPDB ID: AMPDB_4232

Protein Names: Osmotin (CpOsm)

Protein Family: Thaumatin family

Gene Name: Nil

Source Organism: Calotropis procera (Roostertree) (Asclepias procera)

Protein Length: 40 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

ATFTIRNNCPYTIWAAAVPGGGRRLNSGGTWTINVAPGTA

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 6, 'R': 3, 'N': 4, 'D': 0, 'C': 1, 'Q': 0, 'E': 0, 'G': 6, 'H': 0, 'I': 3, 'L': 1, 'K': 0, 'M': 0, 'F': 1, 'P': 3, 'S': 1, 'T': 6, 'W': 2, 'Y': 1, 'V': 2

Frequencies of Amino Acids

'A': 15%, 'R': 7.5%, 'N': 10%, 'D': 0%, 'C': 2.5%, 'Q': 0%, 'E': 0%, 'G': 15%, 'H': 0%, 'I': 7.5%, 'L': 2.5%, 'K': 0%, 'M': 0%, 'F': 2.5%, 'P': 7.5%, 'S': 2.5%, 'T': 15%, 'W': 5%, 'Y': 2.5%, 'V': 5%

Missing Amino Acid(s)

D, E, H, K, M, Q

Most Occurring Amino Acid(s)

A, G, T

Less Occurring Amino Acid(s)

C, F, L, S, Y

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	4133.66 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	68.5	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	35.58	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.025	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.515	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	11.06	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	2.935	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.25, 0.35, 0.175 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.1	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	12490, 12490	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

C.gloeosporioides, F.solani (Gram-positive), Neurospora

4.2 Antimicrobial Activity

Antimicrobial, Fungicide, Plant defense, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: de Freitas CD, Nogueira FC, Vasconcelos IM, et al. Osmotin purified from the latex of Calotropis procera: biochemical characterization, biological activity and role in plant defense. Plant Physiol Biochem. 2011;49(7):738-43. Published 2011 Jul. doi:10.1016/j.plaphy.2011.01.027

PMID: 21334906

5.2 Protein Sequence Databases

UniProt: P86363

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: P86363

5.4 Nucleotide Sequence Databases

No entries found in GenBank or EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR037176, IPR001938

PANTHER: PTHR31048

PROSITE: PS51367

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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