AMPDB_4141 | Pelovaterin

PEPTIDE SUMMARY

Pelovaterin

1 General Description

AMPDB ID: AMPDB_4141

Protein Names: Pelovaterin

Protein Family: Nil

Gene Name: Nil

Source Organism: Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)

Protein Length: 42 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

DDTPSSRCGSGGWGPCLPIVDLLCIVHVTVGCSGGFGCCRIG

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 0, 'R': 2, 'N': 0, 'D': 3, 'C': 6, 'Q': 0, 'E': 0, 'G': 9, 'H': 1, 'I': 3, 'L': 3, 'K': 0, 'M': 0, 'F': 1, 'P': 3, 'S': 4, 'T': 2, 'W': 1, 'Y': 0, 'V': 4

Frequencies of Amino Acids

'A': 0%, 'R': 4.76%, 'N': 0%, 'D': 7.14%, 'C': 14.29%, 'Q': 0%, 'E': 0%, 'G': 21.43%, 'H': 2.38%, 'I': 7.14%, 'L': 7.14%, 'K': 0%, 'M': 0%, 'F': 2.38%, 'P': 7.14%, 'S': 9.52%, 'T': 4.76%, 'W': 2.38%, 'Y': 0%, 'V': 9.52%

Missing Amino Acid(s)

A, E, K, M, N, Q, Y

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

F, H, W

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	4195.85 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	83.333	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	21.998	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.545	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.303	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	5.471	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-1.282	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.286, 0.381, 0.071 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.048	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	5500, 5875	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

Proteus (Gram-negative), Pseudomonas aeruginosa (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Anti-gram-negative

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Lakshminarayanan R, Chi-Jin EO, Loh XJ, et al. Purification and characterization of a vaterite-inducing peptide, pelovaterin, from the eggshells of Pelodiscus sinensis (Chinese soft-shelled turtle). Biomacromolecules. 2005;6(3):1429-37. Published 2005 May-Jun. doi:10.1021/bm049276f

PMID: 15877362

Citation 2: Lakshminarayanan R, Vivekanandan S, Samy RP, et al. Structure, self-assembly, and dual role of a beta-defensin-like peptide from the Chinese soft-shelled turtle eggshell matrix. J Am Chem Soc. 2008;130(14):4660-8. Published 2008 Apr 9. doi:10.1021/ja075659k

PMID: 18341335

5.2 Protein Sequence Databases

UniProt: P84818

5.3 3D Structure Databases

	Sl. no.	PDB ID	Method	Resolution	Access Links	3D View

AlphaFoldDB: P84818

5.4 Nucleotide Sequence Databases

No entries found in GenBank or EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR041579

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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