AMPDB_4090 | Subpeptin JM4-B

PEPTIDE SUMMARY

Subpeptin JM4-B

1 General Description

AMPDB ID: AMPDB_4090

Protein Names: Subpeptin JM4-B

Protein Family: Nil

Gene Name: Nil

Source Organism: Bacillus subtilis

Protein Length: 12 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

XXKEIXHIFHDN

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 0, 'R': 0, 'N': 1, 'D': 1, 'C': 0, 'Q': 0, 'E': 1, 'G': 0, 'H': 2, 'I': 2, 'L': 0, 'K': 1, 'M': 0, 'F': 1, 'P': 0, 'S': 0, 'T': 0, 'W': 0, 'Y': 0, 'V': 0

Frequencies of Amino Acids

'A': 0%, 'R': 0%, 'N': 8.33%, 'D': 8.33%, 'C': 0%, 'Q': 0%, 'E': 8.33%, 'G': 0%, 'H': 16.67%, 'I': 16.67%, 'L': 0%, 'K': 8.33%, 'M': 0%, 'F': 8.33%, 'P': 0%, 'S': 0%, 'T': 0%, 'W': 0%, 'Y': 0%, 'V': 0%

Missing Amino Acid(s)

A, C, G, L, M, P, Q, R, S, T, V, W, Y

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

D, E, F, K, N

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

{'X': 3}

Modified Amino Acid(s) Frequencies

{'X': 0.25}

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	1152.27 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	65	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	61.833	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.75	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.515	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	6.5	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-0.818	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.25, 0.083, 0.083 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.083	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	0, 0	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

B.cereus (Gram-positive), B.megaterium, C.crenatum (Gram-positive), C.glutamicum (Gram-positive), E.faecalis (Gram-positive), L.casei (Gram-positive), L.mesenteroides (Gram-positive), L.viridescens, M.flavus (Not characterize), S.aureus (Gram-positive), S.flexneri (Gram-negative), Salmonella (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Wu S, Jia S, Sun D, et al. Purification and characterization of two novel antimicrobial peptides Subpeptin JM4-A and Subpeptin JM4-B produced by Bacillus subtilis JM4. Curr Microbiol. 2005;51(5):292-6. Published 2005 Nov. doi:10.1007/s00284-005-0004-3

PMID: 16211432

5.2 Protein Sequence Databases

UniProt: P83879

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: P83879

5.4 Nucleotide Sequence Databases

No entries found in GenBank or EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: Not found

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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