AMPDB_38663 | Type VI secretion system effector; Hcp1 family

PEPTIDE SUMMARY

Type VI secretion system effector; Hcp1 family

1 General Description

AMPDB ID: AMPDB_38663

Protein Names: Type VI secretion system effector; Hcp1 family

Protein Family: Nil

Gene Name: HMPREF3212_04813

Source Organism: Citrobacter freundii

Protein Length: 547 AA

Protein Existence: Predicted

2 Protein Sequence & Composition

2.1 Sequence

MGDLIYLKITGEQQGNISSGCGTSASVGNRWQKNHPDEIFVFSLSNGLANTDSGINTQLLNFTKLIDKSTPLLINAINNNERLFIEIDLWRINRFGRWERFYYIQLRNASVKSIQTYVALNELDTEEIAVSYDYILCKHLIANTEFDYLALPAEYNRLFIPPRPQPVSTIKPIVKRPSPPAPHIPAVTPVYAKSCLKEKGCTDAGSREESAENFGQMAVFAQSSVDDCCGYAQPAEASAALPILGGLTQVWGEWSLSGMLSAARGVPYIGALASALYIPSAGTGSARVPGRDEFWYEEELRKKALVGGTATTRVRFFWGTDIHGKSQVYGVHTGEGTPYENVRVANMLWNDEHHRYEFTPAHDAHGPLITWMPENPATGDLPTHTGSNVPPLDQPTILVTPIPDGKNEYTTPPFLVPDVADFNDYILVFPADSGIQPIYVYLSERKTSYTHRHKHYPSKNRPWEEVIKNTKSGPAKFKPEVHIESVDQDVWENGTPTTNGQNWKVKEFNNVQGAYKGKETKWVVTKESQGTIHSHPIGSNEARKLTK

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 39, 'R': 23, 'N': 32, 'D': 24, 'C': 6, 'Q': 18, 'E': 36, 'G': 41, 'H': 16, 'I': 34, 'L': 38, 'K': 30, 'M': 5, 'F': 19, 'P': 41, 'S': 36, 'T': 39, 'W': 13, 'Y': 23, 'V': 34

Frequencies of Amino Acids

'A': 7.13%, 'R': 4.2%, 'N': 5.85%, 'D': 4.39%, 'C': 1.1%, 'Q': 3.29%, 'E': 6.58%, 'G': 7.5%, 'H': 2.93%, 'I': 6.22%, 'L': 6.95%, 'K': 5.48%, 'M': 0.91%, 'F': 3.47%, 'P': 7.5%, 'S': 6.58%, 'T': 7.13%, 'W': 2.38%, 'Y': 4.2%, 'V': 6.22%

Missing Amino Acid(s)

No Amino Acid(s) are missing in this protein

Most Occurring Amino Acid(s)

G, P

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

264

Hydrophilic Amino Acid(s) Count

283

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	60951.6 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	76.49	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	36.218	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.454	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.687	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	6.616	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-5.873	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.294, 0.274, 0.216 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.101	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	105770, 106145	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

No PMID found

5.2 Protein Sequence Databases

UniProt: A0A133L5T6

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A133L5T6

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	LRPR01000042	GenBank \|\| EMBL

CCDS: Not found

RefSeq: WP_060855598.1

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR036624, IPR016128, IPR036302, IPR008514

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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