AMPDB_38482 | Colicin pyocin immunity family protein

PEPTIDE SUMMARY

Colicin pyocin immunity family protein

1 General Description

AMPDB ID: AMPDB_38482

Protein Names: Colicin pyocin immunity family protein

Protein Family: Colicin pyosin nuclease family

Gene Name: YpsIP31758_0164

Source Organism: Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)

Protein Length: 601 AA

Protein Existence: Inferred from homology

2 Protein Sequence & Composition

2.1 Sequence

MLYYEPEFLGSLRQEAYNTYEIAKTEREVAERNRVQKKPFGLFIEEMTLQKTLTDSQVAETAAHIILLESTLTLLRQEEGQAWHQCEHLIRIRGNKKFKYLHEVHGLRKLAQAKQGEIDVINQSIAKLKTEEMGLLMQQQRVNADLETAKITEPQRVENARLTVEAAEKAARDRRISEEIAATEAKRQRMENERLAEQERQRVEGTKQQVSEASCAQQASAWQNRFTLPALQPSGSAQYSFAASGMSAVVLSLREAAELHNSFLAAQEQLSAIATISASGSVAAMIALGIYQTKVGESSERPPGWNVNPKFVGSISLSAMGLPATESLASQGEMALPVRMRIIDAKDWIGCTEIYAVKTGVAGVLPKVKVGAVQYDESTGVYTFTTDSTPPRTLIFTPAQPPGAETRPILAPPGSTPATLQHTGEMIIKPVITPTILPLPQLYARDFHDYIIWFPADSGLEPVYVYLKSPRDEPGVVTGHGERITGIWLAGAGKDMGGPIPAQIADKLRGRQFSHFGRFRAAFWKVVGEDPNLVKYFKSGNLGNIKNGKAPSPKEREQVGRRVKYELHHLKPISKNGAVYHIENIRVLTPKRHMDIHKGVE

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 62, 'R': 38, 'N': 17, 'D': 16, 'C': 3, 'Q': 35, 'E': 52, 'G': 43, 'H': 15, 'I': 38, 'L': 49, 'K': 36, 'M': 13, 'F': 17, 'P': 35, 'S': 35, 'T': 36, 'W': 7, 'Y': 17, 'V': 37

Frequencies of Amino Acids

'A': 10.32%, 'R': 6.32%, 'N': 2.83%, 'D': 2.66%, 'C': 0.5%, 'Q': 5.82%, 'E': 8.65%, 'G': 7.15%, 'H': 2.5%, 'I': 6.32%, 'L': 8.15%, 'K': 5.99%, 'M': 2.16%, 'F': 2.83%, 'P': 5.82%, 'S': 5.82%, 'T': 5.99%, 'W': 1.16%, 'Y': 2.83%, 'V': 6.16%

Missing Amino Acid(s)

No Amino Acid(s) are missing in this protein

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

301

Hydrophilic Amino Acid(s) Count

300

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	66658.2 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	84.626	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	45.609	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.383	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.594	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	9.19	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	7.25	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.275, 0.216, 0.293 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.068	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	63830, 63955	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Hydrolase

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Eppinger M, Rosovitz MJ, Fricke WF, et al. The complete genome sequence of Yersinia pseudotuberculosis IP31758, the causative agent of Far East scarlet-like fever. PLoS Genet. 2007;3(8):e142. Published 2007 Aug. doi:10.1371/journal.pgen.0030142

PMID: 17784789

5.2 Protein Sequence Databases

UniProt: A0A0U1QWS2

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A0U1QWS2

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	CP000720	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR037146, IPR044925, IPR003615, IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: ypi:YpsIP31758_0164

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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