AMPDB_3824 | Antibacterial peptide enbocin

PEPTIDE SUMMARY

Antibacterial peptide enbocin

1 General Description

AMPDB ID: AMPDB_3824

Protein Names: Antibacterial peptide enbocin (Moricin)

Protein Family: Cecropin family

Gene Name: Nil

Source Organism: Bombyx mori (Silk moth)

Protein Length: 59 AA

Protein Existence: Inferred from homology

2 Protein Sequence & Composition

2.1 Sequence

MNFTRIIFFLFVVVFATASGKPWNIFKEIERAVARTRDAVISAGPAVRTVAAATSVASG

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 11, 'R': 5, 'N': 2, 'D': 1, 'C': 0, 'Q': 0, 'E': 2, 'G': 3, 'H': 0, 'I': 5, 'L': 1, 'K': 2, 'M': 1, 'F': 6, 'P': 2, 'S': 4, 'T': 5, 'W': 1, 'Y': 0, 'V': 8

Frequencies of Amino Acids

'A': 18.64%, 'R': 8.47%, 'N': 3.39%, 'D': 1.69%, 'C': 0%, 'Q': 0%, 'E': 3.39%, 'G': 5.08%, 'H': 0%, 'I': 8.47%, 'L': 1.69%, 'K': 3.39%, 'M': 1.69%, 'F': 10.17%, 'P': 3.39%, 'S': 6.78%, 'T': 8.47%, 'W': 1.69%, 'Y': 0%, 'V': 13.56%

Missing Amino Acid(s)

C, H, Q, Y

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

D, L, M, W

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	6330.4 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	97.627	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	25.046	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.654	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.87	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	11.965	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	4.001	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.356, 0.186, 0.254 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.119	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	5500, 5500	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

Gram Negative Bacteria and Gram Positive Bacteria

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Anti-gram-negative, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

No PMID found

5.2 Protein Sequence Databases

UniProt: P48821

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: P48821

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	U30289	GenBank \|\| EMBL
2.	AF049237	GenBank \|\| EMBL

CCDS: Not found

RefSeq: NP_001037472.1

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR000875

PANTHER: Not found

PROSITE: PS00268

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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