AMPDB_38059 | Cytotoxic

PEPTIDE SUMMARY

Cytotoxic

1 General Description

AMPDB ID: AMPDB_38059

Protein Names: Cytotoxic

Protein Family: Nil

Gene Name: ERYG_03177

Source Organism: Escherichia coli M114

Protein Length: 466 AA

Protein Existence: Predicted

2 Protein Sequence & Composition

2.1 Sequence

MGTGYFLVRGDKTTCGGKIIEGADDHTIMGIPQARDMDRVTCGKHSGMFIIVGGVPETDIHGRLMAGSLDSQSSCPCKARFIASMMDDVYETGGGDSGEDDQDDSNNGKATGQNIPTIKKEFTPENDDPSVTPVFAKSCLRGSGCTDAGTESEPVDNFGEMSFYQAAAAAGTITHTGASESAGSTVLRLIGKAASRVLPGRLAVPNPVTVGVIGIFWSEGLNKGEEDYLNNIRLTQLATLQGTAPTRVRFQWVTNAITGKPEIRGYHTGSDGQISDQVPVRMLTPNVGHKDLYEFWESGAKGPSILWTPDNPGYAPPSDTGNDDVFVPPPSVLIYPLPTDTGSSTEILPMPEEKDFRDYILVHPTGDFDPIYVVLSSPHKYFTPPQTNPPLPAFPDAKKAPRKTVIQGGGGLRARWKDSKGKIYEWDSQHGTVEVYDKSGRRHLGEFDPATGKQTKPADPTRRVEK

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 29, 'R': 22, 'N': 14, 'D': 37, 'C': 6, 'Q': 14, 'E': 23, 'G': 53, 'H': 10, 'I': 25, 'L': 24, 'K': 25, 'M': 10, 'F': 16, 'P': 40, 'S': 31, 'T': 39, 'W': 6, 'Y': 13, 'V': 29

Frequencies of Amino Acids

'A': 6.22%, 'R': 4.72%, 'N': 3%, 'D': 7.94%, 'C': 1.29%, 'Q': 3%, 'E': 4.94%, 'G': 11.37%, 'H': 2.15%, 'I': 5.36%, 'L': 5.15%, 'K': 5.36%, 'M': 2.15%, 'F': 3.43%, 'P': 8.58%, 'S': 6.65%, 'T': 8.37%, 'W': 1.29%, 'Y': 2.79%, 'V': 6.22%

Missing Amino Acid(s)

No Amino Acid(s) are missing in this protein

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

C, W

Hydrophobic Amino Acid(s) Count

232

Hydrophilic Amino Acid(s) Count

234

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	50205.2 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	65.279	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	42.787	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.514	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.797	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	5.2	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-12.426	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.242, 0.296, 0.185 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.075	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	52370, 52745	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

No PMID found

5.2 Protein Sequence Databases

UniProt: A0A0K9TCB7

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A0K9TCB7

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	AEMV01000028	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR036725, IPR009105, IPR008727, IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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