AMPDB_3803 | Bacteriocin mesentericin Y105

PEPTIDE SUMMARY

Bacteriocin mesentericin Y105

1 General Description

AMPDB ID: AMPDB_3803

Protein Names: Bacteriocin mesentericin Y105

Protein Family: Bacteriocin class IIA YGNGV family

Gene Name: mesY

Source Organism: Leuconostoc mesenteroides

Protein Length: 61 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MTNMKSVEAYQQLDNQNLKKVVGGKYYGNGVHCTKSGCSVNWGEAASAGIHRLANGGNGFW

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 5, 'R': 1, 'N': 7, 'D': 1, 'C': 2, 'Q': 3, 'E': 2, 'G': 10, 'H': 2, 'I': 1, 'L': 3, 'K': 5, 'M': 2, 'F': 1, 'P': 0, 'S': 4, 'T': 2, 'W': 2, 'Y': 3, 'V': 5

Frequencies of Amino Acids

'A': 8.2%, 'R': 1.64%, 'N': 11.48%, 'D': 1.64%, 'C': 3.28%, 'Q': 4.92%, 'E': 3.28%, 'G': 16.39%, 'H': 3.28%, 'I': 1.64%, 'L': 4.92%, 'K': 8.2%, 'M': 3.28%, 'F': 1.64%, 'P': 0%, 'S': 6.56%, 'T': 3.28%, 'W': 3.28%, 'Y': 4.92%, 'V': 8.2%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

D, F, I, R

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	6548.32 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	57.541	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	-0.905	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.536	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.551	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	9.24	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	3.056	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.246, 0.344, 0.197 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.098	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	15470, 15595	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

Listeria (Gram-positive)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-listeria, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Fremaux C, HÃ©chard Y, Cenatiempo Y, et al. Mesentericin Y105 gene clusters in Leuconostoc mesenteroides Y105. Microbiology (Reading). 1995;141 ( Pt 7):1637-45. Published 1995 Jul. doi:10.1099/13500872-141-7-1637

PMID: 7551032

Citation 2: HÃ©chard Y, DÃ©rijard B, Letellier F, et al. Characterization and purification of mesentericin Y105, an anti-Listeria bacteriocin from Leuconostoc mesenteroides. J Gen Microbiol. 1992;138(12):2725-31. Published 1992 Dec. doi:10.1099/00221287-138-12-2725

PMID: 1487737

5.2 Protein Sequence Databases

UniProt: P38577

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: P38577

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	X81803	GenBank \|\| EMBL

CCDS: Not found

RefSeq: WP_032490739.1

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR002633, IPR023384, IPR023388

PANTHER: Not found

PROSITE: PS60030

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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