AMPDB_3599 | Caerin-1.17
PEPTIDE SUMMARY
Caerin-1.17
1 General Description
AMPDB ID: AMPDB_3599
Protein Names: Caerin-1.17 [Cleaved into: Caerin-1.17.1; Caerin-1.17.2]
Protein Family: Frog skin active peptide (FSAP) family; Caerin subfamily
Gene Name: Nil
Protein Length: 25 AA
Protein Existence: Evidence at protein level
2 Protein Sequence & Composition
2.1 Sequence
GLFSVLGSVAKHLLPHVAPIIAEKL
FASTA format
2.2 Composition
Counts of Amino Acids
'A': 3, 'R': 0, 'N': 0, 'D': 0, 'C': 0, 'Q': 0, 'E': 1, 'G': 2, 'H': 2, 'I': 2, 'L': 5, 'K': 2, 'M': 0, 'F': 1, 'P': 2, 'S': 2, 'T': 0, 'W': 0, 'Y': 0, 'V': 3
Frequencies of Amino Acids
'A': 12%, 'R': 0%, 'N': 0%, 'D': 0%, 'C': 0%, 'Q': 0%, 'E': 4%, 'G': 8%, 'H': 8%, 'I': 8%, 'L': 20%, 'K': 8%, 'M': 0%, 'F': 4%, 'P': 8%, 'S': 8%, 'T': 0%, 'W': 0%, 'Y': 0%, 'V': 12%
Missing Amino Acid(s)
C, D, M, N, Q, R, T, W, Y
Most Occurring Amino Acid(s)
L
Less Occurring Amino Acid(s)
E, F
Hydrophobic Amino Acid(s) Count
18
Hydrophilic Amino Acid(s) Count
7
Basic Amino Acid(s) Count
1
Acidic Amino Acid(s) Count
4
Modified Amino Acid(s) Count
0
Modified Amino Acid(s) Frequencies
0
Computed by biopython (version 1.79) & proteinAnalysis (version 1)
3 Physicochemical Properties
Sl. No. Properties Values Reference
1. Molecular Mass 2610.18 Da Computed by ProtParam module (biopython 1.79)
2. Aliphatic Index 156 Computed by ProtParam module (biopython 1.79)
3. Instability Index (Half Life) 21.612 Computed by ProtParam module (biopython 1.79)
4. Hydrophobicity (GRAVY) 1.02 Computed by ProtParam module (biopython 1.79)
5. Hydrophobic Moment 0.472 Computed by ProtParam module (biopython 1.79)
6. Isoelectric Point 9.541 Computed by ProtParam module (biopython 1.79)
7. Charge (at pH 7) 1.181 Computed by ProtParam module (biopython 1.79)
8. Secondary Structure Fraction 0.44, 0.24, 0.36 [Helix, Turn, Sheet] Computed by ProtParam module (biopython 1.79)
9. Aromaticity 0.04 Computed by ProtParam module (biopython 1.79)
10. Molar Extinction Coefficient (cysteine|cystine) 0, 0 Computed by ProtParam module (biopython 1.79)
4 Activity Details
4.1 Target Organism(s)
Gram Negative Bacteria and Gram Positive Bacteria
4.2 Antimicrobial Activity
Amphibian defense peptide, Antibiotic, Antimicrobial, Anti-gram-negative, Anti-gram-Positive
4.3 Enzymatic Activity
Not found
4.4 Inhibitory Effect
Not found
4.5 Other Biological Activity
Non-hemolytic, Non-ribosomal
Activity data manually curated from Literature and UniProt
5 Database Cross-references
5.1 Literature Database
5.1.1 PubMed
Citation 1: Maclean MJ, Brinkworth CS, Bilusich D, et al. New caerin antibiotic peptides from the skin secretion of the Dainty Green Tree Frog Litoria gracilenta. Identification using positive and negative ion electrospray mass spectrometry. Toxicon. 2006;47(6):664-75. Published 2006 May. doi:10.1016/j.toxicon.2006.01.019
PMID: 16554081
5.2 Protein Sequence Databases
UniProt: P0C2A6
5.3 3D Structure Databases
No PDB Ids found
AlphaFoldDB: P0C2A6
5.4 Nucleotide Sequence Databases
No entries found in GenBank or EMBL
CCDS: Not found
RefSeq: Not found
5.5 Protein-Protein Interaction Databases
STRING: Not found
IntAct: Not found
MINT: Not found
DIP: Not found
BioGRID: Not found
5.6 Ligand Databases
BindingDB: Not found
DrugBank: Not found
ChEMBL: Not found
5.7 Family & Domain Databases
InterPro: IPR010000
PANTHER: Not found
PROSITE: Not found
5.8 Genome Annotation Databases
Ensembl: Not found
KEGG: Not found
5.9 Phylogenomic Databases
GeneTree: Not found
5.10 Enzyme & Pathway Databases
BRENDA: Not found
BioCyc: Not found
5.11 Protein-RNA Interaction Databases
RNAct: Not found




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