AMPDB_35945 | Halocin-S8

PEPTIDE SUMMARY

Halocin-S8

1 General Description

AMPDB ID: AMPDB_35945

Protein Names: Halocin-S8

Protein Family: Nil

Gene Name: halS8

Source Organism: Haloarchaeon S8a

Protein Length: 311 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MSDKDSINRRNVLRKIGGIGVASAVGFSGLASGESLSDDEKQDVIDTIYKSQRVEQIKKKFGGVNIEPKKVQSVTTNQSGDLVTAKLSVSDGDLVYSSVKDTTVIVQFDRSASEIGESWPKNTEAFIKSTSSGVDLLRTATDEEIKDVTEGVNTSEIESADAVNIFIDPESQTYYMEKYDFNNKVLEMFELATGGTSSGKISPTREDQNHEYNVREHKVFNSEKQNIQLQSDCNINSNTAADVILCFNQVGSCALCSPTLVGGPVPTVACLLVVCFGTPNAVSAILEEVDNSCFNLIKDVISCWDEWTSFW

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 16, 'R': 8, 'N': 20, 'D': 23, 'C': 8, 'Q': 12, 'E': 23, 'G': 20, 'H': 2, 'I': 21, 'L': 18, 'K': 20, 'M': 3, 'F': 12, 'P': 8, 'S': 35, 'T': 21, 'W': 4, 'Y': 6, 'V': 31

Frequencies of Amino Acids

'A': 5.14%, 'R': 2.57%, 'N': 6.43%, 'D': 7.4%, 'C': 2.57%, 'Q': 3.86%, 'E': 7.4%, 'G': 6.43%, 'H': 0.64%, 'I': 6.75%, 'L': 5.79%, 'K': 6.43%, 'M': 0.96%, 'F': 3.86%, 'P': 2.57%, 'S': 11.25%, 'T': 6.75%, 'W': 1.29%, 'Y': 1.93%, 'V': 9.97%

Missing Amino Acid(s)

No Amino Acid(s) are missing in this protein

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

133

Hydrophilic Amino Acid(s) Count

178

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	33962.8 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	82.958	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	51.613	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.28	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.717	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	4.283	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-18.276	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.296, 0.267, 0.193 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.071	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	30940, 31440	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

Halobacterium

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Price LB, Shand RF, Shand RF. Halocin S8: a 36-amino-acid microhalocin from the haloarchaeal strain S8a. J Bacteriol. 2000;182(17):4951-8. Published 2000 Sep. doi:10.1128/JB.182.17.4951-4958.2000

PMID: 10940040

5.2 Protein Sequence Databases

UniProt: Q9HHA8

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: Q9HHA8

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	AF276080	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR006311

PANTHER: Not found

PROSITE: PS51318

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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