AMPDB_3590 | Mastoparan-like peptide 12a

PEPTIDE SUMMARY

Mastoparan-like peptide 12a

1 General Description

AMPDB ID: AMPDB_3590

Protein Names: Mastoparan-like peptide 12a

Protein Family: MCD family; Mastoparan subfamily

Gene Name: Nil

Source Organism: Vespa magnifica (Hornet)

Protein Length: 14 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

INWKGIAAMAKKLL

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 3, 'R': 0, 'N': 1, 'D': 0, 'C': 0, 'Q': 0, 'E': 0, 'G': 1, 'H': 0, 'I': 2, 'L': 2, 'K': 3, 'M': 1, 'F': 0, 'P': 0, 'S': 0, 'T': 0, 'W': 1, 'Y': 0, 'V': 0

Frequencies of Amino Acids

'A': 21.43%, 'R': 0%, 'N': 7.14%, 'D': 0%, 'C': 0%, 'Q': 0%, 'E': 0%, 'G': 7.14%, 'H': 0%, 'I': 14.29%, 'L': 14.29%, 'K': 21.43%, 'M': 7.14%, 'F': 0%, 'P': 0%, 'S': 0%, 'T': 0%, 'W': 7.14%, 'Y': 0%, 'V': 0%

Missing Amino Acid(s)

C, D, E, F, H, P, Q, R, S, T, V, Y

Most Occurring Amino Acid(s)

A, K

Less Occurring Amino Acid(s)

G, M, N, W

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	1556.97 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	132.857	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	-7.5	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.529	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.556	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	11.103	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	2.997	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.357, 0.143, 0.429 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.071	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	5500, 5500	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

C.albicans, E.coli (Gram-negative), S.aureus (Gram-positive)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Fungicide, Anti-candida, Anti-gram-negative, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Cytolysis, Hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Xu X, Li J, Lu Q, et al. Two families of antimicrobial peptides from wasp (Vespa magnifica) venom. Toxicon. 2006;47(2):249-53. Published 2006 Feb. doi:10.1016/j.toxicon.2005.10.015

PMID: 16330062

Citation 2: Xu X, Yang H, Yu H, et al. The mastoparanogen from wasp. Peptides. 2006;27(12):3053-7. Published 2006 Dec. doi:10.1016/j.peptides.2006.09.003

PMID: 17046111

5.2 Protein Sequence Databases

UniProt: P0C1M4

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: P0C1M4

5.4 Nucleotide Sequence Databases

No entries found in GenBank or EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR013213

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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