AMPDB_35813 | Cecropin-B2

PEPTIDE SUMMARY

Cecropin-B2

1 General Description

AMPDB ID: AMPDB_35813

Protein Names: Cecropin-B2

Protein Family: Cecropin family

Gene Name: CECB2

Source Organism: Culex pipiens pipiens (Northern house mosquito)

Protein Length: 59 AA

Protein Existence: Inferred from homology

2 Protein Sequence & Composition

2.1 Sequence

MNFNKLFLIVILAALLLLGQTEAGRSKKLGKKIEKAGKRVFNAAQKGLPVAAGVQALGR

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 9, 'R': 3, 'N': 3, 'D': 0, 'C': 0, 'Q': 3, 'E': 2, 'G': 7, 'H': 0, 'I': 3, 'L': 10, 'K': 8, 'M': 1, 'F': 3, 'P': 1, 'S': 1, 'T': 1, 'W': 0, 'Y': 0, 'V': 4

Frequencies of Amino Acids

'A': 15.25%, 'R': 5.08%, 'N': 5.08%, 'D': 0%, 'C': 0%, 'Q': 5.08%, 'E': 3.39%, 'G': 11.86%, 'H': 0%, 'I': 5.08%, 'L': 16.95%, 'K': 13.56%, 'M': 1.69%, 'F': 5.08%, 'P': 1.69%, 'S': 1.69%, 'T': 1.69%, 'W': 0%, 'Y': 0%, 'V': 6.78%

Missing Amino Acid(s)

C, D, H, W, Y

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

M, P, S, T

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	6261.6 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	120.847	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	34.702	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.275	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.842	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	11.895	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	8.999	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.339, 0.203, 0.373 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.051	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	0, 0	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

Gram Negative Bacteria and Gram Positive Bacteria

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Anti-gram-negative, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

No PMID found

5.2 Protein Sequence Databases

UniProt: Q86PR4

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: Q86PR4

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	AY189810	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR000875, IPR020400

PANTHER: PTHR38329

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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