AMPDB_3533 | Defensin J1-2

PEPTIDE SUMMARY

Defensin J1-2

1 General Description

AMPDB ID: AMPDB_3533

Protein Names: Defensin J1-2

Protein Family: DEFL family

Gene Name: Nil

Source Organism: Capsicum annuum (Capsicum pepper)

Protein Length: 74 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

MAGFSKVIATIFLMMMLVFATGMVAEARTCESQSHRFKGLCFSKSNCGSVCHTEGFNGGHCRGFRRRCFCTRHC

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 5, 'R': 7, 'N': 2, 'D': 0, 'C': 8, 'Q': 1, 'E': 3, 'G': 8, 'H': 4, 'I': 2, 'L': 3, 'K': 3, 'M': 5, 'F': 8, 'P': 0, 'S': 6, 'T': 5, 'W': 0, 'Y': 0, 'V': 4

Frequencies of Amino Acids

'A': 6.76%, 'R': 9.46%, 'N': 2.7%, 'D': 0%, 'C': 10.81%, 'Q': 1.35%, 'E': 4.05%, 'G': 10.81%, 'H': 5.41%, 'I': 2.7%, 'L': 4.05%, 'K': 4.05%, 'M': 6.76%, 'F': 10.81%, 'P': 0%, 'S': 8.11%, 'T': 6.76%, 'W': 0%, 'Y': 0%, 'V': 5.41%

Missing Amino Acid(s)

D, P, W, Y

Most Occurring Amino Acid(s)

C, F, G

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	8248.72 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	48.784	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	43.003	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.13	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.571	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	9.044	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	6.87	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.23, 0.216, 0.216 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.108	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	0, 500	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

F.oxysporum

4.2 Antimicrobial Activity

Antimicrobial, Fungicide, Plant defense

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Meyer B, HoulnÃ© G, Pozueta-Romero J, et al. Fruit-specific expression of a defensin-type gene family in bell pepper. Upregulation during ripening and upon wounding. Plant Physiol. 1996;112(2):615-22. Published 1996 Oct. doi:10.1104/pp.112.2.615

PMID: 8883377

Citation 2: HoulnÃ© G, Meyer B, Schantz R, et al. Alteration of the expression of a plant defensin gene by exon shuffling in bell pepper (Capsicum annuum L.). Mol Gen Genet. 1998;259(5):504-10. Published 1998 Sep. doi:10.1007/s004380050841

PMID: 9790581

5.2 Protein Sequence Databases

UniProt: O65740

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: O65740

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	X95730	GenBank \|\| EMBL

CCDS: Not found

RefSeq: XP_016537481.1

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR008176, IPR003614, IPR036574

PANTHER: Not found

PROSITE: PS00940

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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