AMPDB_35183 | Bacteriocin mutacin F-59.1

PEPTIDE SUMMARY

Bacteriocin mutacin F-59.1

1 General Description

AMPDB ID: AMPDB_35183

Protein Names: Bacteriocin mutacin F-59.1

Protein Family: Bacteriocin class IIA YGNGV family

Gene Name: Nil

Source Organism: Streptococcus mutans

Protein Length: 25 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

KYYGNGVTCGKHSXSVDWSKATTNI

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 1, 'R': 0, 'N': 2, 'D': 1, 'C': 1, 'Q': 0, 'E': 0, 'G': 3, 'H': 1, 'I': 1, 'L': 0, 'K': 3, 'M': 0, 'F': 0, 'P': 0, 'S': 3, 'T': 3, 'W': 1, 'Y': 2, 'V': 2

Frequencies of Amino Acids

'A': 4%, 'R': 0%, 'N': 8%, 'D': 4%, 'C': 4%, 'Q': 0%, 'E': 0%, 'G': 12%, 'H': 4%, 'I': 4%, 'L': 0%, 'K': 12%, 'M': 0%, 'F': 0%, 'P': 0%, 'S': 12%, 'T': 12%, 'W': 4%, 'Y': 8%, 'V': 8%

Missing Amino Acid(s)

E, F, L, M, P, Q, R

Most Occurring Amino Acid(s)

G, K, S, T

Less Occurring Amino Acid(s)

A, C, D, H, I, W, X

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

{'X': 1}

Modified Amino Acid(s) Frequencies

{'X': 0.04}

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	2616.89 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	42.8	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	0.492	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.696	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.347	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	9.254	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	2.025	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.24, 0.32, 0.04 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.12	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	8480, 8480	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

Bacillus (Gram-positive), Enterococcus (Gram-positive), Listeria (Gram-positive), Staphylococcus spp. (Gram-positive), Streptococcus (Gram-positive)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-listeria, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Nicolas GG, LaPointe G, Lavoie MC, et al. Production, purification, sequencing and activity spectra of mutacins D-123.1 and F-59.1. BMC Microbiol. 2011;11:69. Published 2011 Apr 10. doi:10.1186/1471-2180-11-69

PMID: 21477375

5.2 Protein Sequence Databases

UniProt: P86386

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: P86386

5.4 Nucleotide Sequence Databases

No entries found in GenBank or EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR002633, IPR023388

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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