AMPDB_35140 | Bacteriocin thuricin-S

PEPTIDE SUMMARY

Bacteriocin thuricin-S

1 General Description

AMPDB ID: AMPDB_35140

Protein Names: Bacteriocin thuricin-S

Protein Family: Nil

Gene Name: Nil

Source Organism: Bacillus thuringiensis subsp. entomocidus

Protein Length: 18 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

DWTXWSXLVXAACSVELL

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 2, 'R': 0, 'N': 0, 'D': 1, 'C': 1, 'Q': 0, 'E': 1, 'G': 0, 'H': 0, 'I': 0, 'L': 3, 'K': 0, 'M': 0, 'F': 0, 'P': 0, 'S': 2, 'T': 1, 'W': 2, 'Y': 0, 'V': 2

Frequencies of Amino Acids

'A': 11.11%, 'R': 0%, 'N': 0%, 'D': 5.56%, 'C': 5.56%, 'Q': 0%, 'E': 5.56%, 'G': 0%, 'H': 0%, 'I': 0%, 'L': 16.67%, 'K': 0%, 'M': 0%, 'F': 0%, 'P': 0%, 'S': 11.11%, 'T': 5.56%, 'W': 11.11%, 'Y': 0%, 'V': 11.11%

Missing Amino Acid(s)

F, G, H, I, K, M, N, P, Q, R, Y

Most Occurring Amino Acid(s)

L, X

Less Occurring Amino Acid(s)

C, D, E, T

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

{'X': 3}

Modified Amino Acid(s) Frequencies

{'X': 0.16666666666666666}

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	1692.95 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	108.333	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	25.506	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.822	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.316	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	3.55	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-2.062	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.389, 0.111, 0.333 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.111	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	11000, 11000	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

B.subtilis (Gram-positive), Bacillus (Gram-positive), E.cloacae (Gram-negative), L.acidophilus (Gram-positive), L.lactis (Gram-positive), L.monocytogenes (Gram-positive), P.acidilactici (Gram-positive), S.flexneri (Gram-negative), S.thermophilus (Gram-positive)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Chehimi S, Delalande F, SablÃ© S, et al. Purification and partial amino acid sequence of thuricin S, a new anti-Listeria bacteriocin from Bacillus thuringiensis. Can J Microbiol. 2007;53(2):284-90. Published 2007 Feb. doi:10.1139/w06-116

PMID: 17496978

5.2 Protein Sequence Databases

UniProt: P84763

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: P84763

5.4 Nucleotide Sequence Databases

No entries found in GenBank or EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: Not found

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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