AMPDB_35132 | Antibacterial napin
PEPTIDE SUMMARY
Antibacterial napin
1 General Description
AMPDB ID: AMPDB_35132
Protein Names: Antibacterial napin [Cleaved into: Napin small chain; Napin large chain]
Protein Family: 2S seed storage albumins family
Gene Name: Nil
Protein Length: 20 AA
Protein Existence: Evidence at protein level
2 Protein Sequence & Composition
2.1 Sequence
PAQPFRFPKHPQGPQTRPPI
FASTA format
2.2 Composition
Counts of Amino Acids
'A': 1, 'R': 2, 'N': 0, 'D': 0, 'C': 0, 'Q': 3, 'E': 0, 'G': 1, 'H': 1, 'I': 1, 'L': 0, 'K': 1, 'M': 0, 'F': 2, 'P': 7, 'S': 0, 'T': 1, 'W': 0, 'Y': 0, 'V': 0
Frequencies of Amino Acids
'A': 5%, 'R': 10%, 'N': 0%, 'D': 0%, 'C': 0%, 'Q': 15%, 'E': 0%, 'G': 5%, 'H': 5%, 'I': 5%, 'L': 0%, 'K': 5%, 'M': 0%, 'F': 10%, 'P': 35%, 'S': 0%, 'T': 5%, 'W': 0%, 'Y': 0%, 'V': 0%
Missing Amino Acid(s)
C, D, E, L, M, N, S, V, W, Y
Most Occurring Amino Acid(s)
P
Less Occurring Amino Acid(s)
A, G, H, I, K, T
Hydrophobic Amino Acid(s) Count
12
Hydrophilic Amino Acid(s) Count
8
Basic Amino Acid(s) Count
0
Acidic Amino Acid(s) Count
4
Modified Amino Acid(s) Count
0
Modified Amino Acid(s) Frequencies
0
Computed by biopython (version 1.79) & proteinAnalysis (version 1)
3 Physicochemical Properties
Sl. No. Properties Values Reference
1. Molecular Mass 2296.66 Da Computed by ProtParam module (biopython 1.79)
2. Aliphatic Index 24.5 Computed by ProtParam module (biopython 1.79)
3. Instability Index (Half Life) 85.1 Computed by ProtParam module (biopython 1.79)
4. Hydrophobicity (GRAVY) -1.35 Computed by ProtParam module (biopython 1.79)
5. Hydrophobic Moment 0.396 Computed by ProtParam module (biopython 1.79)
6. Isoelectric Point 12.517 Computed by ProtParam module (biopython 1.79)
7. Charge (at pH 7) 3.089 Computed by ProtParam module (biopython 1.79)
8. Secondary Structure Fraction 0.15, 0.4, 0.05 [Helix, Turn, Sheet] Computed by ProtParam module (biopython 1.79)
9. Aromaticity 0.1 Computed by ProtParam module (biopython 1.79)
10. Molar Extinction Coefficient (cysteine|cystine) 0, 0 Computed by ProtParam module (biopython 1.79)
4 Activity Details
4.1 Target Organism(s)
B.cereus (Gram-positive), B.megaterium, B.subtilis (Gram-positive), E.coli (Gram-negative), P.fluorescens (Gram-negative), S.aureus (Gram-positive)
4.2 Antimicrobial Activity
Antibiotic, Antimicrobial, Anti-gram-negative, Anti-gram-Positive
4.3 Enzymatic Activity
Not found
4.4 Inhibitory Effect
Protein synthesis inhibitor
4.5 Other Biological Activity
Non-hemolytic, Non-ribosomal
Activity data manually curated from Literature and UniProt
5 Database Cross-references
5.1 Literature Database
5.1.1 PubMed
Citation 1: Ngai PH, Ng TB, Ng TB. A napin-like polypeptide from dwarf Chinese white cabbage seeds with translation-inhibitory, trypsin-inhibitory, and antibacterial activities. Peptides. 2004;25(2):171-6. Published 2004 Feb. doi:10.1016/j.peptides.2003.12.012
PMID: 15062997
5.2 Protein Sequence Databases
UniProt: P84529
5.3 3D Structure Databases
No PDB Ids found
AlphaFoldDB: P84529
5.4 Nucleotide Sequence Databases
No entries found in GenBank or EMBL
CCDS: Not found
RefSeq: Not found
5.5 Protein-Protein Interaction Databases
STRING: Not found
IntAct: Not found
MINT: Not found
DIP: Not found
BioGRID: Not found
5.6 Ligand Databases
BindingDB: Not found
DrugBank: Not found
ChEMBL: Not found
5.7 Family & Domain Databases
InterPro: Not found
PANTHER: Not found
PROSITE: Not found
5.8 Genome Annotation Databases
Ensembl: Not found
KEGG: Not found
5.9 Phylogenomic Databases
GeneTree: Not found
5.10 Enzyme & Pathway Databases
BRENDA: Not found
BioCyc: Not found
5.11 Protein-RNA Interaction Databases
RNAct: Not found




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