AMPDB_35096 | Antibacterial 6.5 kDa protein
PEPTIDE SUMMARY
Antibacterial 6.5 kDa protein
1 General Description
AMPDB ID: AMPDB_35096
Protein Names: Antibacterial 6.5 kDa protein
Protein Family: Nil
Gene Name: Nil
Protein Length: 30 AA
Protein Existence: Evidence at protein level
2 Protein Sequence & Composition
2.1 Sequence
XXVPYPRPFPRPPIGPRPLPFPGGGRPFQS
FASTA format
2.2 Composition
Counts of Amino Acids
'A': 0, 'R': 4, 'N': 0, 'D': 0, 'C': 0, 'Q': 1, 'E': 0, 'G': 4, 'H': 0, 'I': 1, 'L': 1, 'K': 0, 'M': 0, 'F': 3, 'P': 11, 'S': 1, 'T': 0, 'W': 0, 'Y': 1, 'V': 1
Frequencies of Amino Acids
'A': 0%, 'R': 13.33%, 'N': 0%, 'D': 0%, 'C': 0%, 'Q': 3.33%, 'E': 0%, 'G': 13.33%, 'H': 0%, 'I': 3.33%, 'L': 3.33%, 'K': 0%, 'M': 0%, 'F': 10%, 'P': 36.67%, 'S': 3.33%, 'T': 0%, 'W': 0%, 'Y': 3.33%, 'V': 3.33%
Missing Amino Acid(s)
A, C, D, E, H, K, M, N, T, W
Most Occurring Amino Acid(s)
P
Less Occurring Amino Acid(s)
I, L, Q, S, V, Y
Hydrophobic Amino Acid(s) Count
21
Hydrophilic Amino Acid(s) Count
7
Basic Amino Acid(s) Count
0
Acidic Amino Acid(s) Count
4
Modified Amino Acid(s) Count
{'X': 2}
Modified Amino Acid(s) Frequencies
{'X': 0.06666666666666667}
Computed by biopython (version 1.79) & proteinAnalysis (version 1)
3 Physicochemical Properties
Sl. No. Properties Values Reference
1. Molecular Mass 3084.62 Da Computed by ProtParam module (biopython 1.79)
2. Aliphatic Index 35.667 Computed by ProtParam module (biopython 1.79)
3. Instability Index (Half Life) 106.153 Computed by ProtParam module (biopython 1.79)
4. Hydrophobicity (GRAVY) -0.73 Computed by ProtParam module (biopython 1.79)
5. Hydrophobic Moment 0.521 Computed by ProtParam module (biopython 1.79)
6. Isoelectric Point 12.502 Computed by ProtParam module (biopython 1.79)
7. Charge (at pH 7) 3.997 Computed by ProtParam module (biopython 1.79)
8. Secondary Structure Fraction 0.233, 0.533, 0.033 [Helix, Turn, Sheet] Computed by ProtParam module (biopython 1.79)
9. Aromaticity 0.133 Computed by ProtParam module (biopython 1.79)
10. Molar Extinction Coefficient (cysteine|cystine) 1490, 1490 Computed by ProtParam module (biopython 1.79)
4 Activity Details
4.1 Target Organism(s)
E.coli (Gram-negative), M.luteus (Gram-negative), P.immobilis (Gram-negative)
4.2 Antimicrobial Activity
Antibiotic, Antimicrobial, Anti-gram-negative
4.3 Enzymatic Activity
Not found
4.4 Inhibitory Effect
Not found
4.5 Other Biological Activity
Non-hemolytic, Non-ribosomal
Activity data manually curated from Literature and UniProt
5 Database Cross-references
5.1 Literature Database
5.1.1 PubMed
Citation 1: Schnapp D, Kemp GD, Smith VJ, et al. Purification and characterization of a proline-rich antibacterial peptide, with sequence similarity to bactenecin-7, from the haemocytes of the shore crab, Carcinus maenas. Eur J Biochem. 1996;240(3):532-9. Published 1996 Sep 15. doi:10.1111/j.1432-1033.1996.0532h.x
PMID: 8856051
5.2 Protein Sequence Databases
UniProt: P82964
5.3 3D Structure Databases
No PDB Ids found
AlphaFoldDB: P82964
5.4 Nucleotide Sequence Databases
No entries found in GenBank or EMBL
CCDS: Not found
RefSeq: Not found
5.5 Protein-Protein Interaction Databases
STRING: Not found
IntAct: Not found
MINT: Not found
DIP: Not found
BioGRID: Not found
5.6 Ligand Databases
BindingDB: Not found
DrugBank: Not found
ChEMBL: Not found
5.7 Family & Domain Databases
InterPro: Not found
PANTHER: Not found
PROSITE: Not found
5.8 Genome Annotation Databases
Ensembl: Not found
KEGG: Not found
5.9 Phylogenomic Databases
GeneTree: Not found
5.10 Enzyme & Pathway Databases
BRENDA: Not found
BioCyc: Not found
5.11 Protein-RNA Interaction Databases
RNAct: Not found




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