AMPDB_34963 | Mytimycin

PEPTIDE SUMMARY

Mytimycin

1 General Description

AMPDB ID: AMPDB_34963

Protein Names: Mytimycin

Protein Family: Nil

Gene Name: Nil

Source Organism: Mytilus edulis (Blue mussel)

Protein Length: 33 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

DCCRKPFRKHCWDCTAGTPYYGYSTRNIFGCTC

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 1, 'R': 3, 'N': 1, 'D': 2, 'C': 6, 'Q': 0, 'E': 0, 'G': 3, 'H': 1, 'I': 1, 'L': 0, 'K': 2, 'M': 0, 'F': 2, 'P': 2, 'S': 1, 'T': 4, 'W': 1, 'Y': 3, 'V': 0

Frequencies of Amino Acids

'A': 3.03%, 'R': 9.09%, 'N': 3.03%, 'D': 6.06%, 'C': 18.18%, 'Q': 0%, 'E': 0%, 'G': 9.09%, 'H': 3.03%, 'I': 3.03%, 'L': 0%, 'K': 6.06%, 'M': 0%, 'F': 6.06%, 'P': 6.06%, 'S': 3.03%, 'T': 12.12%, 'W': 3.03%, 'Y': 9.09%, 'V': 0%

Missing Amino Acid(s)

E, L, M, Q, V

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

A, H, I, N, S, W

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	3854.4 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	14.849	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	53.258	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.633	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.593	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	8.376	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	2.715	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.212, 0.212, 0.03 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.182	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	9970, 10345	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

N.crassa

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Fungicide

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Charlet M, Chernysh S, Philippe H, et al. Innate immunity. Isolation of several cysteine-rich antimicrobial peptides from the blood of a mollusc, Mytilus edulis. J Biol Chem. 1996;271(36):21808-13. Published 1996 Sep 6. doi:10.1074/jbc.271.36.21808

PMID: 8702979

5.2 Protein Sequence Databases

UniProt: P81614

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: P81614

5.4 Nucleotide Sequence Databases

No entries found in GenBank or EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: Not found

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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