AMPDB_34705 | Sillucin
PEPTIDE SUMMARY
Sillucin
1 General Description
AMPDB ID: AMPDB_34705
Protein Names: Sillucin
Protein Family: Nil
Gene Name: Nil
Source Organism: Rhizomucor pusillus
Protein Length: 30 AA
Protein Existence: Evidence at protein level
2 Protein Sequence & Composition
2.1 Sequence
ACLPNSCVSKGCCCGBSGYWCRQCGIKYTC
FASTA format
2.2 Composition
Counts of Amino Acids
'A': 1, 'R': 1, 'N': 1, 'D': 0, 'C': 8, 'Q': 1, 'E': 0, 'G': 4, 'H': 0, 'I': 1, 'L': 1, 'K': 2, 'M': 0, 'F': 0, 'P': 1, 'S': 3, 'T': 1, 'W': 1, 'Y': 2, 'V': 1
Frequencies of Amino Acids
'A': 3.33%, 'R': 3.33%, 'N': 3.33%, 'D': 0%, 'C': 26.67%, 'Q': 3.33%, 'E': 0%, 'G': 13.33%, 'H': 0%, 'I': 3.33%, 'L': 3.33%, 'K': 6.67%, 'M': 0%, 'F': 0%, 'P': 3.33%, 'S': 10%, 'T': 3.33%, 'W': 3.33%, 'Y': 6.67%, 'V': 3.33%
Missing Amino Acid(s)
D, E, F, H, M
Most Occurring Amino Acid(s)
C
Less Occurring Amino Acid(s)
A, B, I, L, N, P, Q, R, T, V, W
Hydrophobic Amino Acid(s) Count
10
Hydrophilic Amino Acid(s) Count
19
Basic Amino Acid(s) Count
0
Acidic Amino Acid(s) Count
3
Modified Amino Acid(s) Count
{'B': 1}
Modified Amino Acid(s) Frequencies
{'B': 0.03333333333333333}
Computed by biopython (version 1.79) & proteinAnalysis (version 1)
3 Physicochemical Properties
Sl. No. Properties Values Reference
1. Molecular Mass 3094.66 Da Computed by ProtParam module (biopython 1.79)
2. Aliphatic Index 39 Computed by ProtParam module (biopython 1.79)
3. Instability Index (Half Life) 31.807 Computed by ProtParam module (biopython 1.79)
4. Hydrophobicity (GRAVY) 0.173 Computed by ProtParam module (biopython 1.79)
5. Hydrophobic Moment 0.308 Computed by ProtParam module (biopython 1.79)
6. Isoelectric Point 8.203 Computed by ProtParam module (biopython 1.79)
7. Charge (at pH 7) 2.5 Computed by ProtParam module (biopython 1.79)
8. Secondary Structure Fraction 0.2, 0.3, 0.067 [Helix, Turn, Sheet] Computed by ProtParam module (biopython 1.79)
9. Aromaticity 0.1 Computed by ProtParam module (biopython 1.79)
10. Molar Extinction Coefficient (cysteine|cystine) 8480, 8980 Computed by ProtParam module (biopython 1.79)
4 Activity Details
4.1 Target Organism(s)
Rhizomucor pusillus
4.2 Antimicrobial Activity
Antibiotic, Antimicrobial
4.3 Enzymatic Activity
Not found
4.4 Inhibitory Effect
Not found
4.5 Other Biological Activity
Non-hemolytic, Non-ribosomal
Activity data manually curated from Literature and UniProt
5 Database Cross-references
5.1 Literature Database
5.1.1 PubMed
Citation 1: Bradley WA, Somkuti GA, Somkuti GA. The primary structure of sillucin and antimicrobial peptide from Mucor pusillus. FEBS Lett. 1979;97(1):81-3. Published 1979 Jan 1. doi:10.1016/0014-5793(79)80057-5
PMID: 761621
Citation 2: Qi J, Wu J, Somkuti GA, et al. Determination of the disulfide structure of sillucin, a highly knotted, cysteine-rich peptide, by cyanylation/cleavage mass mapping. Biochemistry. 2001;40(15):4531-8. Published 2001 Apr 17. doi:10.1021/bi002229x
PMID: 11294620
5.2 Protein Sequence Databases
UniProt: P02885
5.3 3D Structure Databases
No PDB Ids found
AlphaFoldDB: P02885
5.4 Nucleotide Sequence Databases
No entries found in GenBank or EMBL
CCDS: Not found
RefSeq: Not found
5.5 Protein-Protein Interaction Databases
STRING: Not found
IntAct: Not found
MINT: Not found
DIP: Not found
BioGRID: Not found
5.6 Ligand Databases
BindingDB: Not found
DrugBank: Not found
ChEMBL: Not found
5.7 Family & Domain Databases
InterPro: Not found
PANTHER: Not found
PROSITE: Not found
5.8 Genome Annotation Databases
Ensembl: Not found
KEGG: Not found
5.9 Phylogenomic Databases
GeneTree: Not found
5.10 Enzyme & Pathway Databases
BRENDA: Not found
BioCyc: Not found
5.11 Protein-RNA Interaction Databases
RNAct: Not found




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