AMPDB_34676 | Styelin-E

PEPTIDE SUMMARY

Styelin-E

1 General Description

AMPDB ID: AMPDB_34676

Protein Names: Styelin-E

Protein Family: Nil

Gene Name: Nil

Source Organism: Styela clava (Sea squirt)

Protein Length: 81 AA

Protein Existence: Evidence at transcript level

2 Protein Sequence & Composition

2.1 Sequence

MQMKATILIVLVALFMIQQSEAGWLRKAAKSVGKFYYKHKYYIKAAWKIGRHALGDMTDEEFQDFMKEVEQAREEELQSRQ

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 9, 'R': 4, 'N': 0, 'D': 3, 'C': 0, 'Q': 7, 'E': 8, 'G': 4, 'H': 2, 'I': 5, 'L': 6, 'K': 9, 'M': 5, 'F': 4, 'P': 0, 'S': 3, 'T': 2, 'W': 2, 'Y': 4, 'V': 4

Frequencies of Amino Acids

'A': 11.11%, 'R': 4.94%, 'N': 0%, 'D': 3.7%, 'C': 0%, 'Q': 8.64%, 'E': 9.88%, 'G': 4.94%, 'H': 2.47%, 'I': 6.17%, 'L': 7.41%, 'K': 11.11%, 'M': 6.17%, 'F': 4.94%, 'P': 0%, 'S': 3.7%, 'T': 2.47%, 'W': 2.47%, 'Y': 4.94%, 'V': 4.94%

Missing Amino Acid(s)

C, N, P

Most Occurring Amino Acid(s)

A, K

Less Occurring Amino Acid(s)

H, T, W

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	9588.16 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	78.395	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	63.809	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.443	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.792	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	9.452	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	2.189	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.309, 0.086, 0.346 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.123	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	16960, 16960	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

Gram Negative Bacteria and Gram Positive Bacteria

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Anti-gram-negative, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Zhao C, Liaw L, Lee IH, et al. cDNA cloning of three cecropin-like antimicrobial peptides (Styelins) from the tunicate, Styela clava. FEBS Lett. 1997;412(1):144-8. Published 1997 Jul 21. doi:10.1016/s0014-5793(97)00769-2

PMID: 9257708

5.2 Protein Sequence Databases

UniProt: O18496

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: O18496

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	Y13270	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR035578

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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