AMPDB_34497 | Colicin E5

PEPTIDE SUMMARY

Colicin E5

1 General Description

AMPDB ID: AMPDB_34497

Protein Names: Colicin E5 (Colicin-E3 (EC 3.1.-.-))

Protein Family: Nil

Gene Name: colicin E5 ceaC SAMEA3710766_04220

Source Organism: Shigella sonnei

Protein Length: 556 AA

Protein Existence: Predicted

2 Protein Sequence & Composition

2.1 Sequence

MSGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGPFKFGLWGVALYGVLPSQIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNNSTPAVQTLSPGVTNNTDKDVRPAGFTQGGNTRDAVIRFPKDSGHNAVYVSVSDVLSPDQVKQRQDEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNSRKSELDAANKTLADAIAEIKQFERFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKADADAALITAMESRKKKEDNKRDAEGKLNDELAKNKGKIPGLKIDQKIRGQMPERGWTEDDIKNTVSNGATGTSFDKRSPKKTPPDYLGRNDPATVYGSPGKYVVVNDRTGEVTQISDKTDPGWVDDSRIQWGNKNDQ

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 60, 'R': 27, 'N': 38, 'D': 43, 'C': 0, 'Q': 23, 'E': 24, 'G': 68, 'H': 8, 'I': 21, 'L': 24, 'K': 35, 'M': 10, 'F': 11, 'P': 32, 'S': 43, 'T': 29, 'W': 9, 'Y': 7, 'V': 44

Frequencies of Amino Acids

'A': 10.79%, 'R': 4.86%, 'N': 6.83%, 'D': 7.73%, 'C': 0%, 'Q': 4.14%, 'E': 4.32%, 'G': 12.23%, 'H': 1.44%, 'I': 3.78%, 'L': 4.32%, 'K': 6.29%, 'M': 1.8%, 'F': 1.98%, 'P': 5.76%, 'S': 7.73%, 'T': 5.22%, 'W': 1.62%, 'Y': 1.26%, 'V': 7.91%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

279

Hydrophilic Amino Acid(s) Count

277

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	58280.3 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	65.306	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	35.643	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.636	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.73	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	6.343	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-4.229	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.209, 0.326, 0.212 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.049	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	59930, 59930	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Endonuclease, Hydrolase, Nuclease

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

No PMID found

5.2 Protein Sequence Databases

UniProt: M1XML4

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: M1XML4

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	HF570109	GenBank \|\| EMBL
2.	UDYI01000185	GenBank \|\| EMBL

CCDS: Not found

RefSeq: WP_015420185.1, YP_007500967.1

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR024575, IPR038233, IPR021964, IPR038234, IPR024566, IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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