AMPDB_3066 | M-poneritoxin-Dq4a

PEPTIDE SUMMARY

M-poneritoxin-Dq4a

1 General Description

AMPDB ID: AMPDB_3066

Protein Names: M-poneritoxin-Dq4a (M-PONTX-Dq4a) (Dinoponeratoxin Dq-3104) (Poneratoxin)

Protein Family: Nil

Gene Name: Nil

Source Organism: Dinoponera quadriceps (South American ant)

Protein Length: 28 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

GLKDWWNKHKDKIVEVVKDSGKAGLNAA

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 3, 'R': 0, 'N': 2, 'D': 3, 'C': 0, 'Q': 0, 'E': 1, 'G': 3, 'H': 1, 'I': 1, 'L': 2, 'K': 6, 'M': 0, 'F': 0, 'P': 0, 'S': 1, 'T': 0, 'W': 2, 'Y': 0, 'V': 3

Frequencies of Amino Acids

'A': 10.71%, 'R': 0%, 'N': 7.14%, 'D': 10.71%, 'C': 0%, 'Q': 0%, 'E': 3.57%, 'G': 10.71%, 'H': 3.57%, 'I': 3.57%, 'L': 7.14%, 'K': 21.43%, 'M': 0%, 'F': 0%, 'P': 0%, 'S': 3.57%, 'T': 0%, 'W': 7.14%, 'Y': 0%, 'V': 10.71%

Missing Amino Acid(s)

C, F, M, P, Q, R, T, Y

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

E, H, I, S

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	3107.56 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	83.571	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	21.654	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.761	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.65	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	10.116	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	2.09	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.286, 0.214, 0.214 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.071	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	11000, 11000	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Anti-yeast, Anti-gram-negative

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Toxin, Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Cologna CT, Cardoso Jdos S, Jourdan E, et al. Peptidomic comparison and characterization of the major components of the venom of the giant ant Dinoponera quadriceps collected in four different areas of Brazil. J Proteomics. 2013;94:413-22. Published 2013 Dec 6. doi:10.1016/j.jprot.2013.10.017

PMID: 24157790

Citation 2: Touchard A, Aili SR, Fox EG, et al. The Biochemical Toxin Arsenal from Ant Venoms. Toxins (Basel). 2016;8(1). Published 2016 Jan 20. doi:10.3390/toxins8010030

PMID: 26805882

5.2 Protein Sequence Databases

UniProt: C0HJH7

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: C0HJH7

5.4 Nucleotide Sequence Databases

No entries found in GenBank or EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: Not found

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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