AMPDB_3004 | Antimicrobial protein BL-A60

PEPTIDE SUMMARY

Antimicrobial protein BL-A60

1 General Description

AMPDB ID: AMPDB_3004

Protein Names: Antimicrobial protein BL-A60

Protein Family: Nil

Gene Name: Nil

Source Organism: Brevibacillus laterosporus (Bacillus laterosporus)

Protein Length: 11 AA

Protein Existence: Evidence at protein level

2 Protein Sequence & Composition

2.1 Sequence

LYKLVKVVLNM

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 0, 'R': 0, 'N': 1, 'D': 0, 'C': 0, 'Q': 0, 'E': 0, 'G': 0, 'H': 0, 'I': 0, 'L': 3, 'K': 2, 'M': 1, 'F': 0, 'P': 0, 'S': 0, 'T': 0, 'W': 0, 'Y': 1, 'V': 3

Frequencies of Amino Acids

'A': 0%, 'R': 0%, 'N': 9.09%, 'D': 0%, 'C': 0%, 'Q': 0%, 'E': 0%, 'G': 0%, 'H': 0%, 'I': 0%, 'L': 27.27%, 'K': 18.18%, 'M': 9.09%, 'F': 0%, 'P': 0%, 'S': 0%, 'T': 0%, 'W': 0%, 'Y': 9.09%, 'V': 27.27%

Missing Amino Acid(s)

A, C, D, E, F, G, H, I, P, Q, R, S, T, W

Most Occurring Amino Acid(s)

L, V

Less Occurring Amino Acid(s)

M, N, Y

Hydrophobic Amino Acid(s) Count

Hydrophilic Amino Acid(s) Count

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	1319.71 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	185.455	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	-8.964	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	1.209	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.601	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	10.248	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	1.997	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.636, 0.091, 0.364 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.091	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	1490, 1490	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

B.cinerea, B.subtilis (Gram-positive), P.capsici (Gram-negative), V.dahliae

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Fungicide, Anti-gram-negative, Anti-gram-Positive

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

Citation 1: Zhao J, Guo L, Zeng H, et al. Purification and characterization of a novel antimicrobial peptide from Brevibacillus laterosporus strain A60. Peptides. 2012;33(2):206-11. Published 2012 Feb. doi:10.1016/j.peptides.2012.01.001

PMID: 22244810

5.2 Protein Sequence Databases

UniProt: B3EWC5

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: B3EWC5

5.4 Nucleotide Sequence Databases

No entries found in GenBank or EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: Not found

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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