AMPDB_274 | Lysozyme C
PEPTIDE SUMMARY
Lysozyme C
1 General Description
AMPDB ID: AMPDB_274
Protein Names: Lysozyme C (EC 3.2.1.17) (1;4-beta-N-acetylmuramidase C)
Protein Family: Glycosyl hydrolase 22 family
Gene Name: Nil
Protein Length: 146 AA
Protein Existence: Evidence at protein level
2 Protein Sequence & Composition
2.1 Sequence
SGKYISWEDSCSYLQLQKYERCELAKALKKGGLADFKGYSLENWICTAFHESGYNTASTNYNPPDKSTDYGIFQINSRWWCNDYKTPRSKNTCNIDCKVLLGDDISPAIKCAKRVVSDPNGMGAWVAWKKYCKGKNLSQWTQGCKL
FASTA format
2.2 Composition
Counts of Amino Acids
'A': 9, 'R': 4, 'N': 10, 'D': 9, 'C': 9, 'Q': 5, 'E': 5, 'G': 11, 'H': 1, 'I': 7, 'L': 10, 'K': 17, 'M': 1, 'F': 3, 'P': 5, 'S': 13, 'T': 7, 'W': 7, 'Y': 9, 'V': 4
Frequencies of Amino Acids
'A': 6.16%, 'R': 2.74%, 'N': 6.85%, 'D': 6.16%, 'C': 6.16%, 'Q': 3.42%, 'E': 3.42%, 'G': 7.53%, 'H': 0.68%, 'I': 4.79%, 'L': 6.85%, 'K': 11.64%, 'M': 0.68%, 'F': 2.05%, 'P': 3.42%, 'S': 8.9%, 'T': 4.79%, 'W': 4.79%, 'Y': 6.16%, 'V': 2.74%
Missing Amino Acid(s)
No Amino Acid(s) are missing in this protein
Most Occurring Amino Acid(s)
K
Less Occurring Amino Acid(s)
H, M
Hydrophobic Amino Acid(s) Count
57
Hydrophilic Amino Acid(s) Count
89
Basic Amino Acid(s) Count
14
Acidic Amino Acid(s) Count
22
Modified Amino Acid(s) Count
0
Modified Amino Acid(s) Frequencies
0
Computed by biopython (version 1.79) & proteinAnalysis (version 1)
3 Physicochemical Properties
Sl. No. Properties Values Reference
1. Molecular Mass 16607.8 Da Computed by ProtParam module (biopython 1.79)
2. Aliphatic Index 59.521 Computed by ProtParam module (biopython 1.79)
3. Instability Index (Half Life) 25.471 Computed by ProtParam module (biopython 1.79)
4. Hydrophobicity (GRAVY) -0.681 Computed by ProtParam module (biopython 1.79)
5. Hydrophobic Moment 0.704 Computed by ProtParam module (biopython 1.79)
6. Isoelectric Point 8.769 Computed by ProtParam module (biopython 1.79)
7. Charge (at pH 7) 6.531 Computed by ProtParam module (biopython 1.79)
8. Secondary Structure Fraction 0.274, 0.267, 0.171 [Helix, Turn, Sheet] Computed by ProtParam module (biopython 1.79)
9. Aromaticity 0.13 Computed by ProtParam module (biopython 1.79)
10. Molar Extinction Coefficient (cysteine|cystine) 51910, 52410 Computed by ProtParam module (biopython 1.79)
4 Activity Details
4.1 Target Organism(s)
E.coli (Gram-negative), S.aureus (Gram-positive)
4.2 Antimicrobial Activity
Antibiotic, Antimicrobial, Bacteriolytic enzyme, Anti-candida, Anti-gram-negative, Anti-gram-Positive
4.3 Enzymatic Activity
Glycosidase, Hydrolase
4.4 Inhibitory Effect
Not found
4.5 Other Biological Activity
Non-hemolytic, Non-ribosomal
Activity data manually curated from Literature and UniProt
5 Database Cross-references
5.1 Literature Database
5.1.1 PubMed
Citation 1: Zhao Y, Jin Y, Lee WH, et al. Purification of a lysozyme from skin secretions of Bufo andrewsi. Comp Biochem Physiol C Toxicol Pharmacol. 2006;142(1-2):46-52. Published 2006 Jan-Feb. doi:10.1016/j.cbpc.2005.10.001
PMID: 16309969
5.2 Protein Sequence Databases
UniProt: P85045
5.3 3D Structure Databases
No PDB Ids found
AlphaFoldDB: P85045
5.4 Nucleotide Sequence Databases
No entries found in GenBank or EMBL
CCDS: Not found
RefSeq: Not found
5.5 Protein-Protein Interaction Databases
STRING: Not found
IntAct: Not found
MINT: Not found
DIP: Not found
BioGRID: Not found
5.6 Ligand Databases
BindingDB: Not found
DrugBank: Not found
ChEMBL: Not found
5.7 Family & Domain Databases
PROSITE: PS00128, PS51348
5.8 Genome Annotation Databases
Ensembl: Not found
KEGG: Not found
5.9 Phylogenomic Databases
GeneTree: Not found
5.10 Enzyme & Pathway Databases
BRENDA: Not found
BioCyc: Not found
5.11 Protein-RNA Interaction Databases
RNAct: Not found




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