AMPDB_26489 | Putative Colicin
PEPTIDE SUMMARY
Putative Colicin
1 General Description
AMPDB ID: AMPDB_26489
Protein Names: Putative Colicin
Protein Family: Colicin pyosin nuclease family
Gene Name: YE5603_17481
Protein Length: 906 AA
Protein Existence: Inferred from homology
2 Protein Sequence & Composition
2.1 Sequence
MGEGHSNVSGHGSRGPTGGVKGGATGFGGGNPNSGNGWGVSQTPYGPIHNYNPSKFGHGSQGGGNRGGNRGNKATAANLAQNPELQAYMAVGGMPAVITLMDGSWGVTLSRLPAVAAYVEGHLARVGSWLMRSSPVGVAVLGMMPSSIAPDPPMGQFFTTPTLPADRVTNIPKETLKTVTDVAVNIRVRDVTEDGVQKAFLIKAPIAIQQVPVIKAVTTTRPSVFIAAVPGITPIHIRVTDTITPIDVSAVKQLAVKPNINPIENADFKEVNSSVGRNTHDAIIVFPDSTDIEPLYLSVIRITNNDELMQEARSIYEIARSEREAAERDVAKPIHSVLGALKLKKTLLEKQVTETVVHITLLESNITLLKQAEAQQWQQREALRWHNGRQTCMHKNKRRELEVSALAKQGEVNTLNQGIAELKAKYETLLMLQRDLDVVKAAEQKRIEDIRLAAEAAERQRVEDARLAAERQRIENTRLMAKIEQKFVEFEQWVAEVREMQRIKDAFRAAGGAESQNKRPIAEAVSNIDKQSAIISRNTFFFPAHPIGSLPLPGFAAGGMGSVTLIPQVAAQLSASLRRVSRRFRKFDTTLSANPLVVIIGAGSSLADDGAVSEQPLLAGSFPLSDIGLSLGTRLSWQAEVDSPVRILMASNDGRTSVYAVKTDTVNVATKVKTGEAQFDKSKGVYIFTSDSQPPRTFIFTPAQPPGLETGSILPPPASVPVFPQHTGTDIQFVAVKPDMIFLAPEESDFHDYIIWFPADSGLEPVYVYLKTPRDVPGIVTGHGQRISGIWLAEAGKGQGAPIPAQIANKLRGRKFSNFDRFREAFWQEVANDPELSGQFIVSNRGRVAVGKAPKVRKIDFLGKRTSFEIHHIKFIKDGGEVYDVDNLRVMTPKKHIETHSKNGDK
FASTA format
2.2 Composition
Counts of Amino Acids
'A': 87, 'R': 56, 'N': 38, 'D': 42, 'C': 1, 'Q': 42, 'E': 52, 'G': 76, 'H': 19, 'I': 61, 'L': 61, 'K': 50, 'M': 17, 'F': 35, 'P': 58, 'S': 58, 'T': 54, 'W': 10, 'Y': 13, 'V': 76
Frequencies of Amino Acids
'A': 9.6%, 'R': 6.18%, 'N': 4.19%, 'D': 4.64%, 'C': 0.11%, 'Q': 4.64%, 'E': 5.74%, 'G': 8.39%, 'H': 2.1%, 'I': 6.73%, 'L': 6.73%, 'K': 5.52%, 'M': 1.88%, 'F': 3.86%, 'P': 6.4%, 'S': 6.4%, 'T': 5.96%, 'W': 1.1%, 'Y': 1.43%, 'V': 8.39%
Missing Amino Acid(s)
No Amino Acid(s) are missing in this protein
Most Occurring Amino Acid(s)
A
Less Occurring Amino Acid(s)
C
Hydrophobic Amino Acid(s) Count
481
Hydrophilic Amino Acid(s) Count
425
Basic Amino Acid(s) Count
94
Acidic Amino Acid(s) Count
125
Modified Amino Acid(s) Count
0
Modified Amino Acid(s) Frequencies
0
Computed by biopython (version 1.79) & proteinAnalysis (version 1)
3 Physicochemical Properties
Sl. No. Properties Values Reference
1. Molecular Mass 98514.4 Da Computed by ProtParam module (biopython 1.79)
2. Aliphatic Index 86.446 Computed by ProtParam module (biopython 1.79)
3. Instability Index (Half Life) 42.275 Computed by ProtParam module (biopython 1.79)
4. Hydrophobicity (GRAVY) -0.26 Computed by ProtParam module (biopython 1.79)
5. Hydrophobic Moment 1.059 Computed by ProtParam module (biopython 1.79)
6. Isoelectric Point 9.864 Computed by ProtParam module (biopython 1.79)
7. Charge (at pH 7) 13.748 Computed by ProtParam module (biopython 1.79)
8. Secondary Structure Fraction 0.283, 0.254, 0.24 [Helix, Turn, Sheet] Computed by ProtParam module (biopython 1.79)
9. Aromaticity 0.064 Computed by ProtParam module (biopython 1.79)
10. Molar Extinction Coefficient (cysteine|cystine) 74370, 74370 Computed by ProtParam module (biopython 1.79)
4 Activity Details
4.1 Target Organism(s)
E.coli (Gram-negative)
4.2 Antimicrobial Activity
Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative
4.3 Enzymatic Activity
Hydrolase
4.4 Inhibitory Effect
Not found
4.5 Other Biological Activity
Non-hemolytic, Non-ribosomal
Activity data manually curated from Literature and UniProt
5 Database Cross-references
5.1 Literature Database
5.1.1 PubMed
Citation 1: Reuter S, Connor TR, Barquist L, et al. Parallel independent evolution of pathogenicity within the genus Yersinia. Proc Natl Acad Sci U S A. 2014;111(18):6768-73. Published 2014 May 6. doi:10.1073/pnas.1317161111
PMID: 24753568
5.2 Protein Sequence Databases
UniProt: A0A7U7FAA5
5.3 3D Structure Databases
No PDB Ids found
AlphaFoldDB: A0A7U7FAA5
5.4 Nucleotide Sequence Databases
Sl. no. Accession(s) Access Link(s)
1. HF933423 GenBank || EMBL
CCDS: Not found
5.5 Protein-Protein Interaction Databases
STRING: Not found
IntAct: Not found
MINT: Not found
DIP: Not found
BioGRID: Not found
5.6 Ligand Databases
BindingDB: Not found
DrugBank: Not found
ChEMBL: Not found
5.7 Family & Domain Databases
PANTHER: Not found
PROSITE: Not found
5.8 Genome Annotation Databases
Ensembl: Not found
KEGG: Not found
5.9 Phylogenomic Databases
GeneTree: Not found
5.10 Enzyme & Pathway Databases
BRENDA: Not found
BioCyc: Not found
5.11 Protein-RNA Interaction Databases
RNAct: Not found




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