AMPDB_259 | Histone H2B 1
PEPTIDE SUMMARY
Histone H2B 1
1 General Description
AMPDB ID: AMPDB_259
Protein Names: Histone H2B 1 (Antibacterial histone-like protein 1) (HLP-1)
Protein Family: Histone H2B family
Gene Name: Nil
Protein Length: 21 AA
Protein Existence: Evidence at protein level
2 Protein Sequence & Composition
2.1 Sequence
MPDPAKTAPKKGSKKAVTKXA
FASTA format
2.2 Composition
Counts of Amino Acids
'A': 4, 'R': 0, 'N': 0, 'D': 1, 'C': 0, 'Q': 0, 'E': 0, 'G': 1, 'H': 0, 'I': 0, 'L': 0, 'K': 6, 'M': 1, 'F': 0, 'P': 3, 'S': 1, 'T': 2, 'W': 0, 'Y': 0, 'V': 1
Frequencies of Amino Acids
'A': 19.05%, 'R': 0%, 'N': 0%, 'D': 4.76%, 'C': 0%, 'Q': 0%, 'E': 0%, 'G': 4.76%, 'H': 0%, 'I': 0%, 'L': 0%, 'K': 28.57%, 'M': 4.76%, 'F': 0%, 'P': 14.29%, 'S': 4.76%, 'T': 9.52%, 'W': 0%, 'Y': 0%, 'V': 4.76%
Missing Amino Acid(s)
C, E, F, H, I, L, N, Q, R, W, Y
Most Occurring Amino Acid(s)
K
Less Occurring Amino Acid(s)
D, G, M, S, V, X
Hydrophobic Amino Acid(s) Count
10
Hydrophilic Amino Acid(s) Count
10
Basic Amino Acid(s) Count
1
Acidic Amino Acid(s) Count
6
Modified Amino Acid(s) Count
{'X': 1}
Modified Amino Acid(s) Frequencies
{'X': 0.047619047619047616}
Computed by biopython (version 1.79) & proteinAnalysis (version 1)
3 Physicochemical Properties
Sl. No. Properties Values Reference
1. Molecular Mass 2054.48 Da Computed by ProtParam module (biopython 1.79)
2. Aliphatic Index 32.857 Computed by ProtParam module (biopython 1.79)
3. Instability Index (Half Life) 37.114 Computed by ProtParam module (biopython 1.79)
4. Hydrophobicity (GRAVY) -1 Computed by ProtParam module (biopython 1.79)
5. Hydrophobic Moment 0.502 Computed by ProtParam module (biopython 1.79)
6. Isoelectric Point 11.102 Computed by ProtParam module (biopython 1.79)
7. Charge (at pH 7) 4.997 Computed by ProtParam module (biopython 1.79)
8. Secondary Structure Fraction 0.048, 0.238, 0.238 [Helix, Turn, Sheet] Computed by ProtParam module (biopython 1.79)
9. Aromaticity 0 Computed by ProtParam module (biopython 1.79)
10. Molar Extinction Coefficient (cysteine|cystine) 0, 0 Computed by ProtParam module (biopython 1.79)
4 Activity Details
4.1 Target Organism(s)
E.coli (Gram-negative)
4.2 Antimicrobial Activity
Antibiotic, Antimicrobial, Fungicide, Anti-gram-negative
4.3 Enzymatic Activity
Not found
4.4 Inhibitory Effect
Not found
4.5 Other Biological Activity
Non-hemolytic, Non-ribosomal
Activity data manually curated from Literature and UniProt
5 Database Cross-references
5.1 Literature Database
5.1.1 PubMed
Citation 1: Robinette D, Wada S, Arroll T, et al. Antimicrobial activity in the skin of the channel catfish Ictalurus punctatus: characterization of broad-spectrum histone-like antimicrobial proteins. Cell Mol Life Sci. 1998;54(5):467-75. Published 1998 May. doi:10.1007/s000180050175
PMID: 9645227
5.2 Protein Sequence Databases
UniProt: P81903
5.3 3D Structure Databases
No PDB Ids found
AlphaFoldDB: P81903
5.4 Nucleotide Sequence Databases
No entries found in GenBank or EMBL
CCDS: Not found
RefSeq: Not found
5.5 Protein-Protein Interaction Databases
STRING: Not found
IntAct: Not found
MINT: Not found
DIP: Not found
BioGRID: Not found
5.6 Ligand Databases
BindingDB: Not found
DrugBank: Not found
ChEMBL: Not found
5.7 Family & Domain Databases
InterPro: Not found
PANTHER: Not found
PROSITE: Not found
5.8 Genome Annotation Databases
Ensembl: Not found
KEGG: Not found
5.9 Phylogenomic Databases
GeneTree: Not found
5.10 Enzyme & Pathway Databases
BRENDA: Not found
BioCyc: Not found
5.11 Protein-RNA Interaction Databases
RNAct: Not found




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