AMPDB_24051 | S-type pyocin domain-containing protein

PEPTIDE SUMMARY

S-type pyocin domain-containing protein

1 General Description

AMPDB ID: AMPDB_24051

Protein Names: S-type pyocin domain-containing protein

Protein Family: Colicin pyosin nuclease family

Gene Name: HRD69_04470

Source Organism: Yersinia mollaretii (strain ATCC 43969 DSM 18520 CIP 103324 CNY 7263 WAIP 204)

Protein Length: 530 AA

Protein Existence: Inferred from homology

2 Protein Sequence & Composition

2.1 Sequence

MSEILHREVIYGRRELTGLGRRHRGKNSAGEGRGHRNHRKGRWVWEPIPAGTDSPNPAAAEEEAVVVADNLPTEVTLSADMAVEAVKTPLVESARQVDETELQVDESARQIDETAEQHRITYERWVAETAERQRVEHQRLVVEASKAQAEQQEAIRQNTYSLSAHPVGNLYPPGFAVAGKGAIALEPEVTQGLGASLRMALFKLSTGTAASMAGPLAVTVAAAFYPVKVDKGLHQSPCWDRPPLAGSIPLSNLGISPATGSAKQDDIELPIRMLIADADGFMEIHAVKTGVAGISAKVKVVAAQYDAHQETYTFTTDHRLPRTFTFTSSGADISMGVPAAASTAPASRHTGGVVIRHAVIHTVLPQPTWEDRDFHDYIIGFPANSGLEPVYVYFKNPRYESGTVSGQGKTVSGLWFAGAARGLGAAIPTAIADQLRGRRFSTFDKFSEAFWAVVGHDPELSRQFKRHNISLMKKRFSPFTPASEKINGRDKFECHHVNTMKEGGAVYDMDNLRIATPKRYIKIQSRNKGE

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 64, 'R': 38, 'N': 14, 'D': 24, 'C': 2, 'Q': 20, 'E': 37, 'G': 43, 'H': 19, 'I': 26, 'L': 31, 'K': 24, 'M': 10, 'F': 19, 'P': 31, 'S': 34, 'T': 34, 'W': 7, 'Y': 13, 'V': 40

Frequencies of Amino Acids

'A': 12.08%, 'R': 7.17%, 'N': 2.64%, 'D': 4.53%, 'C': 0.38%, 'Q': 3.77%, 'E': 6.98%, 'G': 8.11%, 'H': 3.58%, 'I': 4.91%, 'L': 5.85%, 'K': 4.53%, 'M': 1.89%, 'F': 3.58%, 'P': 5.85%, 'S': 6.42%, 'T': 6.42%, 'W': 1.32%, 'Y': 2.45%, 'V': 7.55%

Missing Amino Acid(s)

No Amino Acid(s) are missing in this protein

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

271

Hydrophilic Amino Acid(s) Count

259

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	57900.3 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	75.906	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	42.774	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.384	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.651	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	8.27	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	2.659	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.257, 0.23, 0.268 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.074	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	57870, 57995	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Hydrolase

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

No PMID found

5.2 Protein Sequence Databases

UniProt: A0A7D4TIX6

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A7D4TIX6

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	CP054043	GenBank \|\| EMBL

CCDS: Not found

RefSeq: WP_004876972.1

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR037146, IPR044925, IPR003615, IPR003060, IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: ymo:HRD69_04470

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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