AMPDB_19805 | Colicin E7

PEPTIDE SUMMARY

Colicin E7

1 General Description

AMPDB ID: AMPDB_19805

Protein Names: Colicin E7

Protein Family: Colicin pyosin nuclease family

Gene Name: D4423_22825 D5C52_22905

Source Organism: Salmonella enterica subsp. enterica serovar Isangi

Protein Length: 576 AA

Protein Existence: Inferred from homology

2 Protein Sequence & Composition

2.1 Sequence

MSGGDGRGHNSGAHNTGGNINGGPTGLGGNGGASDGSGWSSENNPWGGGSGSGVHWGGGSGHGNGGGNSNSGGGSNSSVAAPMAFGFPALAAPGAGTLGISVSGEALSAAIADIFAALKGPFKFSAWGIALYGILPSEIAKDDPNMMSKIVTSLPAETVTNVQVSTLPLDQATVSVTKRVTDVVKDTRQHIAVVAGVPMSVPVVNAKPTRTPGVFHASFPGVPSLTVSTVKGLPVSTTLPRGITEDKGRTAVPAGFTFGGGSHEAVIRFPKESGQKPVYVSVTDVLTPAQVKQRQDEEKRLQQEWNDAHPVEVAERNYEQARAELNQANKDVARNQERQAKAVQVYNSRKSELDAANKTLADAKAEIKQFERFAREPMAAGHRMWQMAGLKAQRAQTDVNNKKAAFDAAAKEKSDADVALSSALERRKQKENKEKDAKAKLDKESKRNKPGKATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFSRNNNDRMKVGKAPKTRTQDVSGKRTSFELHHEKPISQNGGVYDMDNISVVTPKRHIDIHRGK

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 61, 'R': 30, 'N': 35, 'D': 32, 'C': 0, 'Q': 22, 'E': 30, 'G': 63, 'H': 13, 'I': 17, 'L': 27, 'K': 52, 'M': 10, 'F': 19, 'P': 32, 'S': 46, 'T': 29, 'W': 8, 'Y': 5, 'V': 45

Frequencies of Amino Acids

'A': 10.59%, 'R': 5.21%, 'N': 6.08%, 'D': 5.56%, 'C': 0%, 'Q': 3.82%, 'E': 5.21%, 'G': 10.94%, 'H': 2.26%, 'I': 2.95%, 'L': 4.69%, 'K': 9.03%, 'M': 1.74%, 'F': 3.3%, 'P': 5.56%, 'S': 7.99%, 'T': 5.03%, 'W': 1.39%, 'Y': 0.87%, 'V': 7.81%

Missing Amino Acid(s)

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

282

Hydrophilic Amino Acid(s) Count

294

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	61349.6 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	63.038	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	38.32	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	-0.682	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.858	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	10.423	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	21.228	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.21, 0.306, 0.222 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.056	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	51450, 51450	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

E.coli (Gram-negative)

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Bacteriocin, Anti-gram-negative

4.3 Enzymatic Activity

Endonuclease, Hydrolase, Nuclease

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

No PMID found

5.2 Protein Sequence Databases

UniProt: A0A5W9MHU3

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A5W9MHU3

5.4 Nucleotide Sequence Databases

Sl. no.	Accession(s)	Access Link(s)
1.	AAHOFD010000043	GenBank \|\| EMBL
2.	AAHOMH010000031	GenBank \|\| EMBL

CCDS: Not found

RefSeq: Not found

5.5 Protein-Protein Interaction Databases

STRING: Not found

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR024575, IPR037146, IPR024566, IPR044925, IPR003615, IPR016128, IPR036302

PANTHER: Not found

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: Not found

KEGG: Not found

5.9 Phylogenomic Databases

GeneTree: Not found

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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